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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPVL
All Species:
36.36
Human Site:
Y431
Identified Species:
57.14
UniProt:
Q9H3G5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3G5
NP_061902.2
476
54164
Y431
S
D
S
E
V
A
G
Y
I
R
Q
A
G
D
F
Chimpanzee
Pan troglodytes
XP_001164449
476
54286
Y431
S
D
N
E
V
A
G
Y
I
R
Q
V
G
D
F
Rhesus Macaque
Macaca mulatta
XP_001087943
476
54082
Y431
S
D
N
E
V
A
G
Y
V
R
Q
V
G
D
F
Dog
Lupus familis
XP_854245
479
54464
Y436
S
D
S
E
V
A
G
Y
V
R
Q
V
G
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3S9
478
54744
Y433
S
D
N
E
V
A
G
Y
V
R
R
V
G
K
F
Rat
Rattus norvegicus
Q4QR71
478
55128
Y433
S
D
D
E
V
A
G
Y
V
R
R
V
G
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511641
917
101198
Y438
S
D
T
E
V
A
G
Y
V
R
Q
V
N
D
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001106312
481
54492
Y438
T
D
T
E
V
A
G
Y
V
R
I
T
G
E
F
Zebra Danio
Brachydanio rerio
NP_954972
478
54496
Y435
S
D
T
E
V
A
G
Y
V
R
Q
V
R
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650836
482
54367
Y443
V
G
K
E
V
A
G
Y
V
K
H
A
G
H
L
Honey Bee
Apis mellifera
NP_001152775
467
53684
K429
N
E
L
A
G
Y
S
K
T
V
D
S
L
T
E
Nematode Worm
Caenorhab. elegans
P52715
454
50097
Y412
V
K
G
Q
I
G
G
Y
V
T
Q
Y
K
G
S
Sea Urchin
Strong. purpuratus
XP_786169
496
56125
F454
S
D
T
E
V
A
G
F
V
R
Q
Y
K
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9Q6
444
49204
H395
Q
R
W
G
N
L
C
H
V
A
V
T
G
A
G
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
Q457
E
T
G
E
E
L
G
Q
V
K
N
Y
G
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
95.8
76.6
N.A.
75.3
74
N.A.
36.6
N.A.
59.4
60.6
N.A.
43.3
47.2
27.5
51.6
Protein Similarity:
100
98.9
98.3
87
N.A.
88.9
87.8
N.A.
43.4
N.A.
76.3
76.7
N.A.
64.9
67.4
45.3
68.5
P-Site Identity:
100
86.6
80
80
N.A.
66.6
66.6
N.A.
73.3
N.A.
60
66.6
N.A.
46.6
0
20
66.6
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
86.6
80
N.A.
86.6
N.A.
86.6
86.6
N.A.
60
20
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
74
0
0
0
7
0
14
0
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
7
0
0
0
0
0
0
0
7
0
0
34
0
% D
% Glu:
7
7
0
80
7
0
0
0
0
0
0
0
0
14
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
74
% F
% Gly:
0
7
14
7
7
7
87
0
0
0
0
0
67
7
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
0
0
14
0
7
0
0
0
0
% I
% Lys:
0
7
7
0
0
0
0
7
0
14
0
0
14
14
0
% K
% Leu:
0
0
7
0
0
14
0
0
0
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
20
0
7
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
7
0
0
0
7
0
0
54
0
0
7
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
67
14
0
7
0
0
% R
% Ser:
60
0
14
0
0
0
7
0
0
0
0
7
0
0
7
% S
% Thr:
7
7
27
0
0
0
0
0
7
7
0
14
0
7
0
% T
% Val:
14
0
0
0
74
0
0
0
80
7
7
47
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
74
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _