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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf65
All Species:
22.12
Human Site:
S125
Identified Species:
48.67
UniProt:
Q9H3J6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3J6
NP_001137377.1
166
18828
S125
V
F
Y
N
G
E
N
S
P
V
H
K
E
K
R
Chimpanzee
Pan troglodytes
XP_509459
166
18781
S125
V
F
Y
N
G
E
N
S
P
V
H
K
E
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543374
440
47856
S399
I
F
Y
N
G
E
N
S
I
V
Y
K
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80VP5
184
20769
S128
V
F
Y
N
G
E
N
S
P
V
H
K
E
K
L
Rat
Rattus norvegicus
NP_001102535
181
20506
S125
V
F
Y
N
G
E
N
S
P
I
H
K
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507092
217
24315
S169
I
F
Y
K
G
E
N
S
Y
I
F
K
A
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5WUX7
156
18166
E120
E
L
L
K
M
K
K
E
S
M
Q
K
K
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725560
146
16763
T114
A
Q
E
Q
R
K
S
T
E
R
R
R
R
Q
E
Honey Bee
Apis mellifera
XP_001119911
149
17278
Q116
D
Q
N
S
L
Q
N
Q
K
E
Q
L
M
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202254
156
17666
R120
K
K
R
E
E
K
K
R
K
T
R
L
K
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05863
155
18178
K116
L
Q
W
H
R
Q
Q
K
R
S
Q
R
R
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
N.A.
32
N.A.
70.6
71.8
N.A.
52.5
N.A.
N.A.
51.8
N.A.
37.3
40.9
N.A.
42.1
Protein Similarity:
100
98.8
N.A.
35
N.A.
78.8
79.5
N.A.
58.5
N.A.
N.A.
66.2
N.A.
54.8
59.6
N.A.
61.4
P-Site Identity:
100
93.3
N.A.
73.3
N.A.
93.3
86.6
N.A.
60
N.A.
N.A.
6.6
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
33.3
N.A.
33.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
0
10
10
10
55
0
10
10
10
0
0
46
0
19
% E
% Phe:
0
55
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
37
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
10
19
0
0
0
0
0
% I
% Lys:
10
10
0
19
0
28
19
10
19
0
0
64
19
64
0
% K
% Leu:
10
10
10
0
10
0
0
0
0
0
0
19
0
10
19
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
10
46
0
0
64
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% P
% Gln:
0
28
0
10
0
19
10
10
0
0
28
0
0
19
19
% Q
% Arg:
0
0
10
0
19
0
0
10
10
10
19
19
19
10
28
% R
% Ser:
0
0
0
10
0
0
10
55
10
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% T
% Val:
37
0
0
0
0
0
0
0
0
37
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
55
0
0
0
0
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _