KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GHITM
All Species:
36.06
Human Site:
S185
Identified Species:
66.11
UniProt:
Q9H3K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3K2
NP_055209.2
345
37205
S185
R
S
I
P
Y
D
Q
S
P
G
P
K
H
L
A
Chimpanzee
Pan troglodytes
XP_001148819
418
45077
S258
R
S
I
P
Y
D
H
S
P
G
P
K
H
L
A
Rhesus Macaque
Macaca mulatta
XP_001090977
366
39538
S206
Q
S
I
P
Y
D
Q
S
P
G
P
K
H
L
A
Dog
Lupus familis
XP_851947
345
37246
S185
Q
S
I
S
Y
D
Q
S
P
G
P
K
H
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91VC9
346
37257
S186
H
S
I
S
Y
E
Q
S
P
G
P
K
H
L
A
Rat
Rattus norvegicus
Q5XIA8
346
37160
S186
Q
S
I
S
Y
E
Q
S
P
G
P
K
H
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509171
346
36976
S186
R
S
I
S
Y
E
Q
S
P
G
P
K
H
L
A
Chicken
Gallus gallus
NP_001026388
351
37135
S185
R
S
I
S
Y
E
N
S
P
A
A
K
H
L
A
Frog
Xenopus laevis
NP_001080095
347
36687
S187
R
S
I
S
Y
D
Q
S
P
G
A
K
H
L
A
Zebra Danio
Brachydanio rerio
NP_956885
341
36021
S181
R
S
V
S
Y
E
H
S
P
V
A
K
H
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392713
339
36259
G176
Q
S
I
P
Y
K
E
G
F
G
A
K
Q
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784467
341
35494
G180
M
S
V
P
Y
A
E
G
V
G
L
K
Q
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A20
256
28150
L102
P
F
I
L
I
W
P
L
H
I
Y
H
Q
K
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
90.1
92.1
N.A.
91.6
89.8
N.A.
81.2
71.7
74.3
62.3
N.A.
N.A.
51.2
N.A.
49.5
Protein Similarity:
100
82
91.8
96.5
N.A.
95.9
95.9
N.A.
89.5
82
84.7
79.1
N.A.
N.A.
70.7
N.A.
67.8
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
86.6
66.6
86.6
53.3
N.A.
N.A.
46.6
N.A.
46.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
86.6
93.3
N.A.
93.3
73.3
86.6
73.3
N.A.
N.A.
66.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
31
0
0
0
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
39
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
39
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
0
77
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
16
0
8
0
0
8
77
0
8
% H
% Ile:
0
0
85
0
8
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
93
0
8
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
8
0
0
85
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
39
0
0
8
0
77
0
54
0
0
0
0
% P
% Gln:
31
0
0
0
0
0
54
0
0
0
0
0
24
0
0
% Q
% Arg:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
93
0
54
0
0
0
77
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
93
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _