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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GHITM
All Species:
24.85
Human Site:
S31
Identified Species:
45.56
UniProt:
Q9H3K2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3K2
NP_055209.2
345
37205
S31
A
S
P
V
V
K
N
S
I
T
K
N
Q
W
L
Chimpanzee
Pan troglodytes
XP_001148819
418
45077
S104
A
S
P
V
V
K
N
S
I
T
K
N
Q
W
L
Rhesus Macaque
Macaca mulatta
XP_001090977
366
39538
S52
A
S
P
V
V
K
N
S
I
T
K
N
Q
W
L
Dog
Lupus familis
XP_851947
345
37246
S31
T
S
P
V
V
K
K
S
I
T
K
N
Q
W
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91VC9
346
37257
S32
A
S
P
L
V
K
N
S
I
T
K
N
Q
W
L
Rat
Rattus norvegicus
Q5XIA8
346
37160
S32
A
S
P
L
V
K
N
S
I
T
K
N
Q
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509171
346
36976
A32
S
P
A
L
R
S
S
A
L
K
T
N
Q
R
L
Chicken
Gallus gallus
NP_001026388
351
37135
S31
A
S
P
A
L
R
N
S
G
I
K
A
F
R
L
Frog
Xenopus laevis
NP_001080095
347
36687
A32
S
P
F
L
R
N
S
A
L
K
T
N
Q
C
I
Zebra Danio
Brachydanio rerio
NP_956885
341
36021
R28
Q
G
P
R
A
L
I
R
S
P
A
L
M
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392713
339
36259
F28
T
P
I
N
S
K
P
F
I
P
R
I
Q
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784467
341
35494
A29
K
S
V
H
P
K
T
A
G
L
A
R
V
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A20
256
28150
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
90.1
92.1
N.A.
91.6
89.8
N.A.
81.2
71.7
74.3
62.3
N.A.
N.A.
51.2
N.A.
49.5
Protein Similarity:
100
82
91.8
96.5
N.A.
95.9
95.9
N.A.
89.5
82
84.7
79.1
N.A.
N.A.
70.7
N.A.
67.8
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
20
46.6
13.3
6.6
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
53.3
60
53.3
6.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
8
8
8
0
0
24
0
0
16
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
54
8
0
8
0
0
8
% I
% Lys:
8
0
0
0
0
62
8
0
0
16
54
0
0
0
0
% K
% Leu:
0
0
0
31
8
8
0
0
16
8
0
8
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
8
0
8
47
0
0
0
0
62
0
8
0
% N
% Pro:
0
24
62
0
8
0
8
0
0
16
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
0
0
0
8
16
8
0
8
0
0
8
8
0
16
8
% R
% Ser:
16
62
0
0
8
8
16
54
8
0
0
0
0
8
0
% S
% Thr:
16
0
0
0
0
0
8
0
0
47
16
0
0
0
8
% T
% Val:
0
0
8
31
47
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _