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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNF1
All Species:
8.79
Human Site:
S435
Identified Species:
17.58
UniProt:
Q9H3M0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3M0
NP_002227.2
494
55584
S435
E
L
M
E
L
N
S
S
S
G
G
E
G
K
T
Chimpanzee
Pan troglodytes
A4K2N8
526
58395
A469
H
F
Y
R
R
Q
K
A
L
E
A
A
V
R
N
Rhesus Macaque
Macaca mulatta
A4K2T1
529
58315
K471
S
H
F
Y
R
R
Q
K
A
L
E
A
A
V
R
Dog
Lupus familis
XP_540081
500
56297
S441
E
L
M
E
L
T
S
S
S
G
G
E
G
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSH7
493
55629
S435
E
L
M
E
L
N
S
S
S
A
E
G
K
P
G
Rat
Rattus norvegicus
P15387
857
95619
N546
T
Q
S
Q
P
I
L
N
T
K
E
M
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517513
492
55332
L433
H
E
L
E
L
M
E
L
N
S
G
E
G
K
V
Chicken
Gallus gallus
O73606
518
58750
R458
S
I
F
H
T
F
S
R
S
Y
S
E
L
K
E
Frog
Xenopus laevis
NP_001079256
898
102391
S528
Q
E
Q
L
N
N
A
S
S
S
P
Q
H
L
S
Zebra Danio
Brachydanio rerio
XP_002664235
484
54969
E426
T
A
A
K
H
E
L
E
L
M
E
L
R
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17970
985
106341
P853
Q
Q
I
Q
Q
K
A
P
N
G
N
G
G
A
T
Honey Bee
Apis mellifera
XP_393546
742
81714
M640
I
V
D
T
G
H
N
M
S
G
V
D
G
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
34
95.1
N.A.
96.3
27.1
N.A.
87.4
29.9
26.1
70.8
N.A.
22.6
30.4
N.A.
N.A.
Protein Similarity:
100
52
52.3
97
N.A.
97.3
39.5
N.A.
91.5
51.3
37.4
81.3
N.A.
34.7
43.4
N.A.
N.A.
P-Site Identity:
100
0
0
86.6
N.A.
60
0
N.A.
40
26.6
20
0
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
13.3
6.6
86.6
N.A.
60
20
N.A.
53.3
33.3
46.6
6.6
N.A.
53.3
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
17
9
9
9
9
17
17
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
25
17
0
34
0
9
9
9
0
9
34
34
0
0
9
% E
% Phe:
0
9
17
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
34
25
17
42
0
9
% G
% His:
17
9
0
9
9
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
9
9
0
9
0
0
9
34
0
% K
% Leu:
0
25
9
9
34
0
17
9
17
9
0
9
9
9
9
% L
% Met:
0
0
25
0
0
9
0
9
0
9
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
25
9
9
17
0
9
0
0
9
9
% N
% Pro:
0
0
0
0
9
0
0
9
0
0
9
0
0
17
0
% P
% Gln:
17
17
9
17
9
9
9
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
9
17
9
0
9
0
0
0
0
9
9
9
% R
% Ser:
17
0
9
0
0
0
34
34
50
17
9
0
0
0
17
% S
% Thr:
17
0
0
9
9
9
0
0
9
0
0
0
0
0
17
% T
% Val:
0
9
0
0
0
0
0
0
0
0
9
0
9
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _