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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATXN3L
All Species:
0.91
Human Site:
S249
Identified Species:
1.67
UniProt:
Q9H3M9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3M9
NP_001129467.1
355
40747
S249
R
E
D
E
H
L
R
S
T
I
E
L
S
M
Q
Chimpanzee
Pan troglodytes
XP_001146788
362
41310
R251
D
E
E
A
D
L
R
R
A
I
Q
L
S
M
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537352
301
34778
R203
L
A
Q
L
K
E
Q
R
V
Q
K
T
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVD2
355
40515
L249
M
E
D
E
E
A
D
L
R
R
A
I
Q
L
S
Rat
Rattus norvegicus
O35815
355
40428
A247
I
D
M
E
D
E
E
A
D
L
R
R
A
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507271
358
40934
L252
M
E
D
E
E
A
D
L
R
R
A
I
Q
L
S
Chicken
Gallus gallus
Q9W689
363
41590
I256
E
A
D
L
R
R
A
I
Q
L
S
M
Q
G
S
Frog
Xenopus laevis
NP_001085659
316
35907
L218
D
L
R
R
A
I
Q
L
S
M
Q
G
G
N
Q
Zebra Danio
Brachydanio rerio
NP_957398
266
30028
E168
S
E
T
T
H
T
A
E
E
P
V
L
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623341
340
38556
E241
K
I
E
K
N
D
E
E
D
D
E
N
A
E
L
Nematode Worm
Caenorhab. elegans
O17850
317
35845
S219
G
S
G
A
P
P
D
S
Q
E
E
K
D
L
A
Sea Urchin
Strong. purpuratus
XP_786733
388
42119
Q284
E
A
S
E
P
V
N
Q
D
E
L
R
R
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M391
280
30674
M182
N
F
P
Q
E
C
P
M
S
S
S
S
E
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
N.A.
61.9
N.A.
66.7
65.9
N.A.
63.6
58.9
43
40
N.A.
N.A.
41.9
32.6
34
Protein Similarity:
100
80.6
N.A.
70.6
N.A.
78.3
78
N.A.
78.4
74.9
60
55.2
N.A.
N.A.
57.1
50.7
52
P-Site Identity:
100
53.3
N.A.
0
N.A.
20
13.3
N.A.
20
6.6
6.6
20
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
66.6
N.A.
26.6
N.A.
33.3
46.6
N.A.
33.3
20
40
20
N.A.
N.A.
40
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
16
8
16
16
8
8
0
16
0
16
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
31
0
16
8
24
0
24
8
0
0
24
0
8
% D
% Glu:
16
39
16
39
24
16
16
16
8
16
24
0
8
16
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
8
8
8
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
0
8
0
16
0
16
0
8
0
% I
% Lys:
8
0
0
8
8
0
0
0
0
0
8
8
0
8
0
% K
% Leu:
8
8
0
16
0
16
0
24
0
16
8
24
0
31
8
% L
% Met:
16
0
8
0
0
0
0
8
0
8
0
8
0
16
0
% M
% Asn:
8
0
0
0
8
0
8
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
8
0
16
8
8
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
16
8
16
8
16
0
24
0
31
% Q
% Arg:
8
0
8
8
8
8
16
16
16
16
8
16
8
0
8
% R
% Ser:
8
8
8
0
0
0
0
16
16
8
16
8
16
0
31
% S
% Thr:
0
0
8
8
0
8
0
0
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _