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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH4
All Species:
6.97
Human Site:
S250
Identified Species:
17.04
UniProt:
Q9H3N8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3N8
NP_001137300.1
390
44496
S250
E
V
P
A
S
F
H
S
E
R
Q
R
R
K
S
Chimpanzee
Pan troglodytes
Q9N2A7
440
48835
N236
L
E
H
N
K
I
Q
N
G
K
A
P
R
D
P
Rhesus Macaque
Macaca mulatta
P56489
460
51414
C260
E
T
P
P
G
R
C
C
R
C
C
R
P
P
R
Dog
Lupus familis
XP_547634
395
45119
L256
E
T
A
P
S
V
P
L
K
R
H
E
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZY2
391
44230
S252
E
S
A
A
S
R
H
S
E
S
P
R
R
K
S
Rat
Rattus norvegicus
Q91ZY1
391
44005
S252
E
P
A
A
S
L
H
S
E
S
P
R
G
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520508
432
48627
R275
Q
R
T
L
D
S
D
R
R
E
D
G
L
C
R
Chicken
Gallus gallus
P49578
639
71958
L363
Y
R
R
C
H
F
W
L
T
M
K
S
W
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001020689
473
53488
S305
V
A
D
L
A
S
R
S
R
C
C
R
L
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
C305
L
L
L
K
Q
V
S
C
K
S
L
N
D
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.2
25.8
71.9
N.A.
68.5
69.5
N.A.
41.4
23.3
N.A.
35.3
N.A.
N.A.
N.A.
24.7
N.A.
Protein Similarity:
100
48.8
45.8
81
N.A.
78.5
79.5
N.A.
55
38.1
N.A.
51.5
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
100
6.6
20
40
N.A.
66.6
60
N.A.
0
6.6
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
20
46.6
N.A.
66.6
60
N.A.
6.6
20
N.A.
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
30
10
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
10
20
0
20
20
0
0
10
0
% C
% Asp:
0
0
10
0
10
0
10
0
0
0
10
0
10
10
0
% D
% Glu:
50
10
0
0
0
0
0
0
30
10
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
0
10
10
0
10
% G
% His:
0
0
10
0
10
0
30
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
20
10
10
0
0
40
0
% K
% Leu:
20
10
10
20
0
10
0
20
0
0
10
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
10
20
20
0
0
10
0
0
0
20
10
10
10
20
% P
% Gln:
10
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
20
10
0
0
20
10
10
30
20
0
50
40
10
20
% R
% Ser:
0
10
0
0
40
20
10
40
0
30
0
10
0
0
50
% S
% Thr:
0
20
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
10
10
0
0
0
20
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _