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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM4C
All Species:
9.7
Human Site:
S457
Identified Species:
23.7
UniProt:
Q9H3R0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3R0
NP_001140166.1
1056
119982
S457
L
S
G
N
S
C
L
S
T
S
V
T
E
D
I
Chimpanzee
Pan troglodytes
XP_001144352
1056
119743
S457
L
S
G
N
S
C
L
S
T
S
V
T
E
D
I
Rhesus Macaque
Macaca mulatta
XP_001112470
1059
120327
S460
L
S
G
N
S
C
L
S
T
S
V
T
E
D
M
Dog
Lupus familis
XP_531930
1053
119366
S454
N
I
K
L
P
G
N
S
C
L
S
T
S
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD7
1054
119947
I455
K
L
S
G
K
G
C
I
S
S
S
V
T
A
E
Rat
Rattus norvegicus
A1A5Q5
510
57169
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507384
1068
120585
Q480
E
E
E
E
E
E
E
Q
E
A
A
A
L
D
L
Chicken
Gallus gallus
XP_422410
1058
119418
E470
L
K
V
V
K
L
E
E
E
E
E
E
E
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076274
1134
127451
K534
G
G
G
V
E
E
I
K
A
D
F
Q
D
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6L0
590
66418
V26
F
K
D
F
P
K
Y
V
A
Y
M
E
S
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.8
89.8
N.A.
84.5
32
N.A.
54.9
55.3
N.A.
48.2
N.A.
32.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.1
94.2
N.A.
90.5
39.9
N.A.
70.2
72.4
N.A.
64.1
N.A.
42.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
6.6
0
N.A.
6.6
13.3
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
0
N.A.
20
13.3
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
10
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
30
10
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
10
40
0
% D
% Glu:
10
10
10
10
20
20
20
10
20
10
10
20
40
0
20
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
10
40
10
0
20
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
10
0
0
0
0
0
10
20
% I
% Lys:
10
20
10
0
20
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
40
10
0
10
0
10
30
0
0
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
10
0
0
30
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
10
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
30
10
0
30
0
0
40
10
40
20
0
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
30
0
0
40
10
0
10
% T
% Val:
0
0
10
20
0
0
0
10
0
0
30
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _