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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA4A All Species: 15.76
Human Site: S731 Identified Species: 34.67
UniProt: Q9H3S1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3S1 NP_071762.2 761 83574 S731 P G E K A P L S R E Q H L Q S
Chimpanzee Pan troglodytes XP_513876 651 71896 Y622 Q D G V G G L Y Q C W A T E N
Rhesus Macaque Macaca mulatta XP_001116428 760 83386 S731 P G E K A P L S R E Q H L Q S
Dog Lupus familis XP_547538 759 82855 S729 P G E K A P L S R E Q H L Q P
Cat Felis silvestris
Mouse Mus musculus Q62178 760 83440 S730 P R E K A P L S R D Q H L Q P
Rat Rattus norvegicus Q9Z143 776 84280 F743 L G K R G S G F G G F P P P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510220 599 64530 H570 L L S P G S P H T S Q H S D R
Chicken Gallus gallus Q90607 772 88849 V743 Q R P A N A Q V N T N K W K H
Frog Xenopus laevis NP_001087062 835 93986 A773 T N V P S P A A D H K G Y Q T
Zebra Danio Brachydanio rerio Q9YHX4 766 85599 S737 H A N D Q R Y S S S R E T D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 S818 P H S S S G S S P V M S N S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 96.8 83.9 N.A. 82.5 32.3 N.A. 40.4 30.1 36.7 31.7 N.A. 29 N.A. N.A. N.A.
Protein Similarity: 100 85.4 98.2 90.2 N.A. 88.3 47 N.A. 50.9 49.6 53.4 50.2 N.A. 45.1 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 80 6.6 N.A. 13.3 0 13.3 6.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 93.3 N.A. 86.6 20 N.A. 13.3 6.6 40 13.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 37 10 10 10 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 0 0 0 10 10 0 0 0 19 0 % D
% Glu: 0 0 37 0 0 0 0 0 0 28 0 10 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 10 % F
% Gly: 0 37 10 0 28 19 10 0 10 10 0 10 0 0 0 % G
% His: 10 10 0 0 0 0 0 10 0 10 0 46 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 37 0 0 0 0 0 0 10 10 0 10 0 % K
% Leu: 19 10 0 0 0 0 46 0 0 0 0 0 37 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 10 10 0 10 0 0 0 10 0 10 0 10 0 10 % N
% Pro: 46 0 10 19 0 46 10 0 10 0 0 10 10 10 19 % P
% Gln: 19 0 0 0 10 0 10 0 10 0 46 0 0 46 0 % Q
% Arg: 0 19 0 10 0 10 0 0 37 0 10 0 0 0 19 % R
% Ser: 0 0 19 10 19 19 10 55 10 19 0 10 10 10 28 % S
% Thr: 10 0 0 0 0 0 0 0 10 10 0 0 19 0 10 % T
% Val: 0 0 10 10 0 0 0 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 10 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _