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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA4A
All Species:
6.97
Human Site:
S738
Identified Species:
15.33
UniProt:
Q9H3S1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S1
NP_071762.2
761
83574
S738
S
R
E
Q
H
L
Q
S
P
K
E
C
R
T
S
Chimpanzee
Pan troglodytes
XP_513876
651
71896
N629
Y
Q
C
W
A
T
E
N
G
F
S
Y
P
V
I
Rhesus Macaque
Macaca mulatta
XP_001116428
760
83386
S738
S
R
E
Q
H
L
Q
S
P
K
E
C
R
T
S
Dog
Lupus familis
XP_547538
759
82855
P736
S
R
E
Q
H
L
Q
P
P
K
E
L
R
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62178
760
83440
P737
S
R
D
Q
H
L
Q
P
S
K
D
H
R
T
S
Rat
Rattus norvegicus
Q9Z143
776
84280
F750
F
G
G
F
P
P
P
F
L
L
D
S
C
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510220
599
64530
R577
H
T
S
Q
H
S
D
R
E
H
S
G
A
L
E
Chicken
Gallus gallus
Q90607
772
88849
H750
V
N
T
N
K
W
K
H
L
Q
E
N
K
K
G
Frog
Xenopus laevis
NP_001087062
835
93986
T780
A
D
H
K
G
Y
Q
T
L
N
D
N
Y
I
I
Zebra Danio
Brachydanio rerio
Q9YHX4
766
85599
R744
S
S
S
R
E
T
D
R
L
S
T
T
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
S825
S
P
V
M
S
N
S
S
S
S
P
A
P
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
96.8
83.9
N.A.
82.5
32.3
N.A.
40.4
30.1
36.7
31.7
N.A.
29
N.A.
N.A.
N.A.
Protein Similarity:
100
85.4
98.2
90.2
N.A.
88.3
47
N.A.
50.9
49.6
53.4
50.2
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
66.6
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
80
13.3
N.A.
13.3
26.6
33.3
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
10
19
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
19
10
0
0
% C
% Asp:
0
10
10
0
0
0
19
0
0
0
28
0
0
0
0
% D
% Glu:
0
0
28
0
10
0
10
0
10
0
37
0
0
0
10
% E
% Phe:
10
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
0
0
0
10
0
0
10
0
10
10
% G
% His:
10
0
10
0
46
0
0
10
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
19
% I
% Lys:
0
0
0
10
10
0
10
0
0
37
0
0
10
10
0
% K
% Leu:
0
0
0
0
0
37
0
0
37
10
0
10
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
10
0
10
0
10
0
19
0
0
0
% N
% Pro:
0
10
0
0
10
10
10
19
28
0
10
0
19
19
0
% P
% Gln:
0
10
0
46
0
0
46
0
0
10
0
0
0
0
0
% Q
% Arg:
0
37
0
10
0
0
0
19
0
0
0
0
37
0
0
% R
% Ser:
55
10
19
0
10
10
10
28
19
19
19
10
0
0
64
% S
% Thr:
0
10
10
0
0
19
0
10
0
0
10
10
0
37
0
% T
% Val:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _