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Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPK1
All Species:
28.79
Human Site:
S62
Identified Species:
48.72
UniProt:
Q9H3S4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S4
NP_071890.2
243
27265
S62
I
T
E
G
E
R
E
S
F
L
P
E
F
I
N
Chimpanzee
Pan troglodytes
XP_519461
243
27275
S62
I
T
E
G
E
R
E
S
F
L
P
E
F
I
N
Rhesus Macaque
Macaca mulatta
XP_001094591
327
35961
S146
I
T
E
G
E
R
E
S
F
L
P
E
F
I
N
Dog
Lupus familis
XP_532737
208
22899
I40
I
S
G
D
F
D
S
I
R
P
E
V
K
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0M5
243
27050
S62
L
T
E
G
E
R
E
S
F
L
P
E
F
V
S
Rat
Rattus norvegicus
NP_001128466
243
27189
S62
L
T
E
G
E
R
E
S
F
L
P
E
F
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506978
182
20341
S14
Y
I
S
G
D
F
D
S
I
R
P
E
V
M
E
Chicken
Gallus gallus
XP_418875
244
26997
S63
I
T
E
G
S
Q
D
S
F
L
P
D
Y
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006074
257
28841
S62
L
T
E
G
R
R
E
S
F
L
P
D
Y
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30636
243
27296
V60
I
L
K
R
K
S
F
V
E
W
P
H
I
I
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302706
255
28531
R75
D
A
L
D
V
R
H
R
Y
K
P
D
M
I
K
Maize
Zea mays
NP_001152100
267
30322
K86
D
K
K
S
T
R
N
K
Y
V
P
E
I
I
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850424
267
30196
R78
D
P
F
V
I
R
N
R
Y
K
P
D
V
I
K
Baker's Yeast
Sacchar. cerevisiae
P35202
319
36598
K88
D
D
E
T
L
R
I
K
Y
L
P
N
Y
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
65.7
76.9
N.A.
89.3
86.8
N.A.
58
73.3
N.A.
59.5
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
100
99.5
69.7
81.8
N.A.
95
93
N.A.
65.8
84.4
N.A.
74.3
N.A.
N.A.
N.A.
51.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
80
93.3
N.A.
26.6
60
N.A.
73.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
46.6
93.3
N.A.
93.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
38.4
36.7
N.A.
36.3
28.5
N.A.
Protein Similarity:
58
57.3
N.A.
55
42.9
N.A.
P-Site Identity:
20
26.6
N.A.
20
33.3
N.A.
P-Site Similarity:
33.3
46.6
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
29
8
0
15
8
8
15
0
0
0
0
29
0
0
0
% D
% Glu:
0
0
58
0
36
0
43
0
8
0
8
50
0
8
15
% E
% Phe:
0
0
8
0
8
8
8
0
50
0
0
0
36
0
0
% F
% Gly:
0
0
8
58
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
43
8
0
0
8
0
8
8
8
0
0
0
15
79
8
% I
% Lys:
0
8
15
0
8
0
0
15
0
15
0
0
8
0
15
% K
% Leu:
22
8
8
0
8
0
0
0
0
58
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
8
0
0
36
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
93
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
72
0
15
8
8
0
0
0
0
0
% R
% Ser:
0
8
8
8
8
8
8
58
0
0
0
0
0
0
15
% S
% Thr:
0
50
0
8
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
8
0
8
0
8
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
29
0
0
0
22
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _