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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPK1
All Species:
27.88
Human Site:
T220
Identified Species:
47.18
UniProt:
Q9H3S4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S4
NP_071890.2
243
27265
T220
T
L
V
S
T
S
N
T
Y
D
G
S
G
V
V
Chimpanzee
Pan troglodytes
XP_519461
243
27275
T220
T
L
V
S
T
S
N
T
Y
D
G
S
G
V
V
Rhesus Macaque
Macaca mulatta
XP_001094591
327
35961
T304
T
L
V
S
T
S
N
T
Y
D
G
S
G
V
V
Dog
Lupus familis
XP_532737
208
22899
Y186
L
V
S
T
S
N
T
Y
D
G
S
G
V
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0M5
243
27050
T220
T
L
V
S
T
S
N
T
Y
D
G
S
G
L
V
Rat
Rattus norvegicus
NP_001128466
243
27189
T220
T
L
V
S
T
S
N
T
Y
D
G
S
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506978
182
20341
Y160
L
V
S
T
S
N
T
Y
D
G
S
D
D
V
T
Chicken
Gallus gallus
XP_418875
244
26997
T221
T
L
V
S
T
S
N
T
Y
D
N
S
G
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006074
257
28841
T220
Q
L
V
S
T
S
N
T
Y
E
D
H
D
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30636
243
27296
E213
K
L
I
S
T
S
N
E
V
T
T
S
Q
V
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302706
255
28531
L232
D
L
V
S
T
S
N
L
V
Q
G
E
K
I
T
Maize
Zea mays
NP_001152100
267
30322
I243
S
M
I
S
T
S
N
I
V
Q
S
E
K
V
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850424
267
30196
L235
G
L
I
S
T
S
N
L
V
K
E
E
I
I
T
Baker's Yeast
Sacchar. cerevisiae
P35202
319
36598
R289
G
R
V
S
S
S
N
R
F
V
G
D
N
C
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
65.7
76.9
N.A.
89.3
86.8
N.A.
58
73.3
N.A.
59.5
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
100
99.5
69.7
81.8
N.A.
95
93
N.A.
65.8
84.4
N.A.
74.3
N.A.
N.A.
N.A.
51.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
6.6
86.6
N.A.
53.3
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
33.3
86.6
N.A.
60
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
38.4
36.7
N.A.
36.3
28.5
N.A.
Protein Similarity:
58
57.3
N.A.
55
42.9
N.A.
P-Site Identity:
46.6
33.3
N.A.
33.3
33.3
N.A.
P-Site Similarity:
53.3
53.3
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
0
0
0
0
0
0
15
43
8
15
15
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
8
8
22
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
15
0
0
0
0
0
0
0
0
15
50
8
43
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
22
0
0
0
0
8
0
0
0
0
8
15
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
8
0
0
15
0
8
% K
% Leu:
15
72
0
0
0
0
0
15
0
0
0
0
0
15
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
86
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
15
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
15
86
22
86
0
0
0
0
22
50
0
0
0
% S
% Thr:
43
0
0
15
79
0
15
50
0
8
8
0
0
8
36
% T
% Val:
0
15
65
0
0
0
0
0
29
8
0
0
8
50
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _