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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPK1
All Species:
15.15
Human Site:
T85
Identified Species:
25.64
UniProt:
Q9H3S4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S4
NP_071890.2
243
27265
T85
E
V
R
E
Y
Y
A
T
K
G
C
E
L
I
S
Chimpanzee
Pan troglodytes
XP_519461
243
27275
T85
E
V
R
E
Y
Y
A
T
K
G
C
E
L
I
S
Rhesus Macaque
Macaca mulatta
XP_001094591
327
35961
T169
E
V
R
E
Y
Y
A
T
K
G
C
E
L
I
S
Dog
Lupus familis
XP_532737
208
22899
H63
I
S
T
P
D
Q
D
H
T
D
F
T
K
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0M5
243
27050
K85
E
V
K
E
Y
Y
T
K
K
G
C
D
L
I
S
Rat
Rattus norvegicus
NP_001128466
243
27189
K85
E
V
K
E
Y
Y
T
K
K
G
C
D
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506978
182
20341
N37
L
I
E
T
A
D
Q
N
F
T
D
F
T
K
C
Chicken
Gallus gallus
XP_418875
244
26997
A86
E
V
K
A
Y
Y
K
A
K
G
C
E
L
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006074
257
28841
G85
E
V
K
A
F
Y
A
G
K
N
C
K
L
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30636
243
27296
K83
Q
I
D
T
K
N
A
K
V
V
H
L
P
D
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302706
255
28531
N98
E
V
L
D
F
Y
T
N
L
G
T
K
V
V
D
Maize
Zea mays
NP_001152100
267
30322
S109
E
V
K
L
F
Y
S
S
Q
G
S
K
I
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850424
267
30196
Y101
D
V
L
D
F
Y
V
Y
W
G
T
K
V
I
D
Baker's Yeast
Sacchar. cerevisiae
P35202
319
36598
K111
K
V
Y
K
Y
Y
R
K
N
K
V
T
I
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
65.7
76.9
N.A.
89.3
86.8
N.A.
58
73.3
N.A.
59.5
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
100
99.5
69.7
81.8
N.A.
95
93
N.A.
65.8
84.4
N.A.
74.3
N.A.
N.A.
N.A.
51.8
N.A.
P-Site Identity:
100
100
100
0
N.A.
73.3
73.3
N.A.
0
66.6
N.A.
46.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
0
N.A.
86.6
86.6
N.A.
6.6
73.3
N.A.
73.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
38.4
36.7
N.A.
36.3
28.5
N.A.
Protein Similarity:
58
57.3
N.A.
55
42.9
N.A.
P-Site Identity:
26.6
26.6
N.A.
26.6
26.6
N.A.
P-Site Similarity:
60
73.3
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
36
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
8
8
% C
% Asp:
8
0
8
15
8
8
8
0
0
8
8
15
0
8
22
% D
% Glu:
65
0
8
36
0
0
0
0
0
0
0
29
0
0
15
% E
% Phe:
0
0
0
0
29
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
65
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
8
15
0
0
0
0
0
0
0
0
0
0
15
58
0
% I
% Lys:
8
0
36
8
8
0
8
29
50
8
0
29
8
8
8
% K
% Leu:
8
0
15
8
0
0
0
0
8
0
0
8
50
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
15
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
22
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
8
8
0
0
8
0
0
8
36
% S
% Thr:
0
0
8
15
0
0
22
22
8
8
15
15
8
0
0
% T
% Val:
0
79
0
0
0
0
8
0
8
8
8
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
50
79
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _