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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPK1
All Species:
25.45
Human Site:
T93
Identified Species:
43.08
UniProt:
Q9H3S4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S4
NP_071890.2
243
27265
T93
K
G
C
E
L
I
S
T
P
D
Q
D
H
T
D
Chimpanzee
Pan troglodytes
XP_519461
243
27275
T93
K
G
C
E
L
I
S
T
P
D
Q
D
H
T
D
Rhesus Macaque
Macaca mulatta
XP_001094591
327
35961
T177
K
G
C
E
L
I
S
T
P
D
Q
D
H
T
D
Dog
Lupus familis
XP_532737
208
22899
E71
T
D
F
T
K
C
L
E
L
L
Q
K
K
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0M5
243
27050
T93
K
G
C
D
L
I
S
T
P
D
Q
D
H
T
D
Rat
Rattus norvegicus
NP_001128466
243
27189
T93
K
G
C
D
L
I
S
T
P
D
Q
D
H
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506978
182
20341
L45
F
T
D
F
T
K
C
L
K
V
L
L
E
K
I
Chicken
Gallus gallus
XP_418875
244
26997
T94
K
G
C
E
L
I
E
T
M
D
Q
D
F
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006074
257
28841
T93
K
N
C
K
L
M
E
T
P
D
Q
D
L
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30636
243
27296
D91
V
V
H
L
P
D
Q
D
Y
T
D
L
S
K
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002302706
255
28531
E106
L
G
T
K
V
V
D
E
S
H
D
Q
D
T
T
Maize
Zea mays
NP_001152100
267
30322
K117
Q
G
S
K
I
S
D
K
S
H
N
Q
E
T
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850424
267
30196
E109
W
G
T
K
V
I
D
E
S
H
D
Q
D
T
T
Baker's Yeast
Sacchar. cerevisiae
P35202
319
36598
Q119
N
K
V
T
I
I
K
Q
T
T
Q
Y
S
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
65.7
76.9
N.A.
89.3
86.8
N.A.
58
73.3
N.A.
59.5
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
100
99.5
69.7
81.8
N.A.
95
93
N.A.
65.8
84.4
N.A.
74.3
N.A.
N.A.
N.A.
51.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
0
80
N.A.
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
0
80
N.A.
80
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
38.4
36.7
N.A.
36.3
28.5
N.A.
Protein Similarity:
58
57.3
N.A.
55
42.9
N.A.
P-Site Identity:
13.3
13.3
N.A.
20
26.6
N.A.
P-Site Similarity:
33.3
33.3
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
50
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
15
0
8
22
8
0
50
22
50
15
0
58
% D
% Glu:
0
0
0
29
0
0
15
22
0
0
0
0
15
0
8
% E
% Phe:
8
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
22
0
0
36
0
0
% H
% Ile:
0
0
0
0
15
58
0
0
0
0
0
0
0
8
8
% I
% Lys:
50
8
0
29
8
8
8
8
8
0
0
8
8
15
0
% K
% Leu:
8
0
0
8
50
0
8
8
8
8
8
15
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
43
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
8
8
0
0
65
22
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
36
0
22
0
0
0
15
0
8
% S
% Thr:
8
8
15
15
8
0
0
50
8
15
0
0
0
79
22
% T
% Val:
8
8
8
0
15
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _