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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGM All Species: 20.26
Human Site: T417 Identified Species: 34.29
UniProt: Q9H3S5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3S5 NP_660150.1 423 49460 T417 H Y K E E P L T E R I K Y D _
Chimpanzee Pan troglodytes XP_001170950 423 49427 T417 H Y K E E P L T E R I K Y D _
Rhesus Macaque Macaca mulatta XP_001117352 423 49476 T417 H Y K E E P L T E R I K Y D _
Dog Lupus familis XP_852677 415 46614 A409 H Y K E E P P A E R V K C D _
Cat Felis silvestris
Mouse Mus musculus Q8C2R7 423 49770 T417 H Y K E D R L T E R I K Y D _
Rat Rattus norvegicus Q9EQY6 423 49575 T417 H Y K E D R L T E R I K Y D _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F380 418 46559 V411 H Y Q Q E T Q V A R K V K E Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T310 392 44391 I381 T F I L A Q I I Q H Y R P H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496426 417 48233
Sea Urchin Strong. purpuratus XP_785711 1003 112336 S709 E E E D E Y E S D E D R G M L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132411 444 50908 F428 H H K Y T L L F S T P L K S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q500W7 450 52928 F434 R H R F S P L F R R Y E S S S
Baker's Yeast Sacchar. cerevisiae P47088 403 47148 P395 D I K I P T Q P T V S N K K N
Red Bread Mold Neurospora crassa Q7S4Z3 487 54011 S457 E L E F L G R S T F L P G L W
Conservation
Percent
Protein Identity: 100 99.7 97.1 74.9 N.A. 89.8 91 N.A. N.A. 60.5 N.A. 52.9 N.A. N.A. N.A. 41.8 22.8
Protein Similarity: 100 100 98.5 82.5 N.A. 94.3 94.8 N.A. N.A. 74.6 N.A. 66.6 N.A. N.A. N.A. 59 29.1
P-Site Identity: 100 100 100 71.4 N.A. 85.7 85.7 N.A. N.A. 26.6 N.A. 0 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 78.5 N.A. 92.8 92.8 N.A. N.A. 46.6 N.A. 26.6 N.A. N.A. N.A. 0 40
Percent
Protein Identity: N.A. 39.4 N.A. 39.1 38.3 37.7
Protein Similarity: N.A. 58.5 N.A. 56.6 58.1 51.7
P-Site Identity: N.A. 20 N.A. 20 6.6 0
P-Site Similarity: N.A. 33.3 N.A. 40 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 0 8 15 0 0 0 8 0 8 0 0 43 8 % D
% Glu: 15 8 15 43 43 0 8 0 43 8 0 8 0 8 0 % E
% Phe: 0 8 0 15 0 0 0 15 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 8 % G
% His: 58 15 0 0 0 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 8 8 8 0 0 8 8 0 0 36 0 0 0 0 % I
% Lys: 0 0 58 0 0 0 0 0 0 0 8 43 22 8 0 % K
% Leu: 0 8 0 8 8 8 50 0 0 0 8 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 8 36 8 8 0 0 8 8 8 0 0 % P
% Gln: 0 0 8 8 0 8 15 0 8 0 0 0 0 0 8 % Q
% Arg: 8 0 8 0 0 15 8 0 8 58 0 15 0 0 0 % R
% Ser: 0 0 0 0 8 0 0 15 8 0 8 0 8 15 8 % S
% Thr: 8 0 0 0 8 15 0 36 15 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 50 0 8 0 8 0 0 0 0 15 0 36 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43 % _