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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGM
All Species:
35.76
Human Site:
Y249
Identified Species:
60.51
UniProt:
Q9H3S5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3S5
NP_660150.1
423
49460
Y249
S
F
G
F
Y
Y
E
Y
G
W
E
F
L
E
H
Chimpanzee
Pan troglodytes
XP_001170950
423
49427
Y249
S
F
G
F
Y
Y
E
Y
G
W
E
F
L
E
H
Rhesus Macaque
Macaca mulatta
XP_001117352
423
49476
Y249
S
F
G
F
Y
Y
E
Y
G
W
E
F
L
E
H
Dog
Lupus familis
XP_852677
415
46614
Y241
S
L
G
F
Y
R
R
Y
G
W
E
F
L
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2R7
423
49770
Y249
S
F
G
F
Y
Y
K
Y
G
W
E
F
L
E
H
Rat
Rattus norvegicus
Q9EQY6
423
49575
Y249
S
F
G
F
Y
Y
K
Y
G
W
E
F
L
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F380
418
46559
Y243
T
V
L
F
Y
H
L
Y
G
W
E
F
L
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7T310
392
44391
R237
A
Y
L
Y
H
L
T
R
R
D
L
R
H
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496426
417
48233
G246
L
F
F
F
Q
I
Y
G
Q
L
F
L
D
E
Y
Sea Urchin
Strong. purpuratus
XP_785711
1003
112336
Y237
T
A
V
M
Y
H
W
Y
G
D
E
F
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132411
444
50908
Y259
T
G
V
F
F
Y
L
Y
G
W
D
F
L
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q500W7
450
52928
Y265
N
A
V
S
F
Y
F
Y
G
Q
E
F
L
H
E
Baker's Yeast
Sacchar. cerevisiae
P47088
403
47148
W244
H
R
H
N
F
S
V
W
N
M
L
L
Y
L
D
Red Bread Mold
Neurospora crassa
Q7S4Z3
487
54011
Y310
N
F
L
M
Y
R
L
Y
G
H
P
F
L
Q
E
Conservation
Percent
Protein Identity:
100
99.7
97.1
74.9
N.A.
89.8
91
N.A.
N.A.
60.5
N.A.
52.9
N.A.
N.A.
N.A.
41.8
22.8
Protein Similarity:
100
100
98.5
82.5
N.A.
94.3
94.8
N.A.
N.A.
74.6
N.A.
66.6
N.A.
N.A.
N.A.
59
29.1
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
0
N.A.
N.A.
N.A.
20
40
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
80
N.A.
26.6
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
39.4
N.A.
39.1
38.3
37.7
Protein Similarity:
N.A.
58.5
N.A.
56.6
58.1
51.7
P-Site Identity:
N.A.
46.6
N.A.
40
0
40
P-Site Similarity:
N.A.
66.6
N.A.
53.3
13.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
15
8
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
22
0
0
0
65
0
0
58
29
% E
% Phe:
0
50
8
65
22
0
8
0
0
0
8
79
0
0
8
% F
% Gly:
0
8
43
0
0
0
0
8
79
0
0
0
0
0
0
% G
% His:
8
0
8
0
8
15
0
0
0
8
0
0
8
8
50
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
22
0
0
8
22
0
0
8
15
15
79
8
0
% L
% Met:
0
0
0
15
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
15
0
0
8
0
0
0
0
8
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
15
8
8
8
0
0
8
0
0
0
% R
% Ser:
43
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% S
% Thr:
22
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
22
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
58
0
0
0
0
0
% W
% Tyr:
0
8
0
8
65
50
8
79
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _