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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGM All Species: 44.24
Human Site: Y74 Identified Species: 74.87
UniProt: Q9H3S5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3S5 NP_660150.1 423 49460 Y74 S P Y L R A T Y R Y T P L L G
Chimpanzee Pan troglodytes XP_001170950 423 49427 Y74 S P Y L R A T Y R Y T P L L G
Rhesus Macaque Macaca mulatta XP_001117352 423 49476 Y74 S P Y L R A T Y R Y T P L L G
Dog Lupus familis XP_852677 415 46614 Y67 S P Y L R A T Y R Y T P L L A
Cat Felis silvestris
Mouse Mus musculus Q8C2R7 423 49770 Y74 S P Y L R A T Y R Y T P L L S
Rat Rattus norvegicus Q9EQY6 423 49575 Y74 S P Y L R A T Y R Y T P L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F380 418 46559 F64 S P Y R R A T F R Y T P L L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T310 392 44391 F61 S P Y R R S T F R Y T P L L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496426 417 48233 Y71 S P F D R A T Y R Y T P A L A
Sea Urchin Strong. purpuratus XP_785711 1003 112336 Y62 S P Y Q R A T Y R Y T P I L A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132411 444 50908 Y65 S P F A R A T Y R Y S P I L A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q500W7 450 52928 Y74 S P Y K R T T Y R Y S P L L A
Baker's Yeast Sacchar. cerevisiae P47088 403 47148 Y61 S P Y A R D T Y R Y T P L L S
Red Bread Mold Neurospora crassa Q7S4Z3 487 54011 Y82 S P Y A R E T Y R Y T P I L A
Conservation
Percent
Protein Identity: 100 99.7 97.1 74.9 N.A. 89.8 91 N.A. N.A. 60.5 N.A. 52.9 N.A. N.A. N.A. 41.8 22.8
Protein Similarity: 100 100 98.5 82.5 N.A. 94.3 94.8 N.A. N.A. 74.6 N.A. 66.6 N.A. N.A. N.A. 59 29.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 80 N.A. 73.3 N.A. N.A. N.A. 73.3 80
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 86.6 N.A. N.A. N.A. 80 86.6
Percent
Protein Identity: N.A. 39.4 N.A. 39.1 38.3 37.7
Protein Similarity: N.A. 58.5 N.A. 56.6 58.1 51.7
P-Site Identity: N.A. 66.6 N.A. 73.3 80 73.3
P-Site Similarity: N.A. 86.6 N.A. 80 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 22 0 72 0 0 0 0 0 0 8 0 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 15 0 0 0 0 15 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 22 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 43 0 0 0 0 0 0 0 0 72 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 100 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 15 100 0 0 0 100 0 0 0 0 0 0 % R
% Ser: 100 0 0 0 0 8 0 0 0 0 15 0 0 0 22 % S
% Thr: 0 0 0 0 0 8 100 0 0 0 86 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 86 0 0 0 0 86 0 100 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _