KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
20.91
Human Site:
S228
Identified Species:
38.33
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
S228
G
I
C
S
E
H
Q
S
R
T
V
A
T
L
S
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
A212
G
M
C
S
G
H
Q
A
R
A
T
V
I
L
H
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
S228
G
I
C
S
E
H
Q
S
R
T
V
A
T
L
S
Dog
Lupus familis
XP_545861
952
103673
S228
G
I
C
S
E
H
Q
S
R
T
V
A
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
S228
G
I
C
S
E
H
Q
S
R
T
V
A
T
L
S
Rat
Rattus norvegicus
Q32PZ3
944
103222
S228
G
I
C
S
E
H
Q
S
R
T
V
A
T
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
E227
W
M
S
V
D
N
E
E
I
S
L
A
V
C
N
Frog
Xenopus laevis
NP_001087472
927
103492
A210
G
M
C
T
G
H
R
A
R
A
T
A
I
V
H
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
A217
G
M
C
T
G
H
R
A
R
A
T
A
I
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
E220
A
L
C
E
N
S
V
E
R
T
K
G
V
L
T
Honey Bee
Apis mellifera
XP_396019
942
106098
N217
E
L
C
K
D
N
I
N
R
T
K
D
I
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
S217
C
L
C
G
G
H
R
S
R
A
T
A
V
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
46.6
100
100
N.A.
100
100
N.A.
N.A.
6.6
33.3
33.3
N.A.
26.6
26.6
N.A.
33.3
P-Site Similarity:
100
60
100
100
N.A.
100
100
N.A.
N.A.
53.3
66.6
66.6
N.A.
40
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
24
0
31
0
70
0
0
8
% A
% Cys:
8
0
85
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
0
8
39
0
8
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
62
0
0
8
31
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
39
0
0
0
0
8
0
8
0
0
0
31
16
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
16
0
0
0
8
% K
% Leu:
0
24
0
0
0
0
0
0
0
0
8
0
0
62
0
% L
% Met:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
16
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
24
0
85
0
0
0
0
0
0
% R
% Ser:
0
0
8
47
0
8
0
47
0
8
0
0
0
0
39
% S
% Thr:
0
0
0
16
0
0
0
0
0
54
31
0
39
0
8
% T
% Val:
0
0
0
8
0
0
8
0
0
0
39
8
24
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _