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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
20.3
Human Site:
S493
Identified Species:
37.22
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
S493
Y
K
C
S
E
K
D
S
I
R
I
R
A
L
V
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
K477
Y
K
T
T
K
N
E
K
I
K
I
R
T
L
V
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
S493
Y
K
R
S
E
K
D
S
I
R
I
R
A
L
V
Dog
Lupus familis
XP_545861
952
103673
S493
Y
K
R
S
E
K
D
S
I
R
I
R
A
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
S493
Y
K
G
S
E
R
D
S
I
R
I
R
A
L
V
Rat
Rattus norvegicus
Q32PZ3
944
103222
S493
Y
K
G
S
E
R
D
S
I
R
I
R
A
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
K468
Y
K
K
T
K
N
E
K
I
K
I
R
A
L
V
Frog
Xenopus laevis
NP_001087472
927
103492
K474
Y
K
K
T
K
N
E
K
I
K
I
R
A
L
V
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
K481
Y
K
K
T
K
N
E
K
I
K
I
R
A
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
G482
L
Y
H
S
K
N
D
G
I
R
V
R
A
L
V
Honey Bee
Apis mellifera
XP_396019
942
106098
S479
L
Y
Q
S
K
D
D
S
I
R
V
R
A
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
H477
L
Y
K
S
P
N
D
H
I
K
V
R
A
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
E125
T
R
K
L
K
E
C
E
K
A
V
M
K
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
46.6
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
53.3
53.3
N.A.
53.3
60
N.A.
46.6
P-Site Similarity:
100
73.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
80
N.A.
66.6
73.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
85
0
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
62
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
39
8
31
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
93
0
70
0
0
0
0
% I
% Lys:
0
70
39
0
54
24
0
31
8
39
0
0
8
0
8
% K
% Leu:
24
0
0
8
0
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
16
0
0
16
0
0
0
54
0
93
0
0
0
% R
% Ser:
0
0
0
62
0
0
0
47
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
31
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
93
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
70
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _