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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
25.45
Human Site:
S578
Identified Species:
46.67
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
S578
L
K
A
L
F
Q
L
S
R
L
E
E
R
S
V
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
A562
L
Q
A
M
F
E
L
A
K
T
S
D
K
T
I
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
S578
L
K
A
L
F
Q
L
S
R
S
E
E
R
S
V
Dog
Lupus familis
XP_545861
952
103673
S578
L
K
A
L
F
Q
L
S
R
S
E
E
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
S578
L
K
A
L
F
Q
L
S
R
S
E
E
R
S
V
Rat
Rattus norvegicus
Q32PZ3
944
103222
S578
L
K
A
L
F
Q
L
S
R
S
E
E
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
A553
L
Q
A
M
F
E
L
A
K
T
S
D
K
T
I
Frog
Xenopus laevis
NP_001087472
927
103492
C559
L
K
A
M
F
E
L
C
K
T
S
D
K
T
I
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
T566
M
R
A
M
F
E
L
T
K
S
N
D
K
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
A567
I
H
A
L
M
D
L
A
R
G
G
N
Q
S
C
Honey Bee
Apis mellifera
XP_396019
942
106098
A564
V
Q
A
M
I
E
L
A
K
T
G
D
Q
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
S562
L
Q
A
L
M
D
L
S
K
T
S
D
K
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
S197
E
I
L
M
V
L
V
S
V
V
L
G
T
F
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
26.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
33.3
20
N.A.
33.3
26.6
N.A.
40
P-Site Similarity:
100
86.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
86.6
N.A.
53.3
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
93
0
0
0
0
31
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
16
0
0
0
0
0
47
0
0
0
% D
% Glu:
8
0
0
0
0
39
0
0
0
0
39
39
0
0
0
% E
% Phe:
0
0
0
0
70
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
16
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
31
% I
% Lys:
0
47
0
0
0
0
0
0
47
0
0
0
39
0
0
% K
% Leu:
70
0
8
54
0
8
93
0
0
8
8
0
0
0
0
% L
% Met:
8
0
0
47
16
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
31
0
0
0
39
0
0
0
0
0
0
16
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
47
0
0
0
39
0
0
% R
% Ser:
0
0
0
0
0
0
0
54
0
39
31
0
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
39
0
0
8
39
0
% T
% Val:
8
0
0
0
8
0
8
0
8
8
0
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _