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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
13.64
Human Site:
S630
Identified Species:
25
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
S630
Q
H
P
K
D
K
P
S
F
V
R
A
R
V
K
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
D614
E
H
P
K
D
K
K
D
F
I
D
M
R
V
K
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
S630
Q
H
P
K
D
K
P
S
F
V
R
A
R
V
K
Dog
Lupus familis
XP_545861
952
103673
G630
Q
H
P
K
D
K
P
G
F
V
R
A
R
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
S630
Q
H
P
K
D
K
P
S
F
V
R
A
R
V
K
Rat
Rattus norvegicus
Q32PZ3
944
103222
S630
Q
H
P
K
D
K
P
S
F
V
R
A
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
D605
E
H
P
K
D
K
K
D
F
V
V
K
R
V
K
Frog
Xenopus laevis
NP_001087472
927
103492
D611
Q
H
P
K
D
K
K
D
F
V
L
K
R
V
K
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
D618
Q
H
P
K
D
K
K
D
F
I
V
R
R
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
D619
E
H
E
L
D
D
V
D
F
I
N
K
R
I
T
Honey Bee
Apis mellifera
XP_396019
942
106098
D616
E
H
E
L
D
D
V
D
F
V
N
K
R
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
N614
E
H
P
K
D
A
T
N
F
I
D
Q
R
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
A249
K
T
L
H
K
R
Y
A
Y
Q
I
V
L
Q
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
60
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
73.3
66.6
N.A.
26.6
33.3
N.A.
46.6
P-Site Similarity:
100
73.3
100
93.3
N.A.
100
100
N.A.
N.A.
73.3
73.3
73.3
N.A.
46.6
46.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
39
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
93
16
0
47
0
0
16
0
0
0
0
% D
% Glu:
39
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
93
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
31
8
0
0
16
0
% I
% Lys:
8
0
0
77
8
70
31
0
0
0
0
31
0
0
77
% K
% Leu:
0
0
8
16
0
0
0
0
0
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
8
% N
% Pro:
0
0
77
0
0
0
39
0
0
0
0
0
0
0
0
% P
% Gln:
54
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
39
8
93
0
0
% R
% Ser:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
16
% T
% Val:
0
0
0
0
0
0
16
0
0
62
16
8
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _