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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
21.21
Human Site:
S854
Identified Species:
38.89
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
S854
S
M
R
P
T
L
C
S
R
I
P
Q
V
T
T
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
L838
A
A
H
K
K
L
C
L
K
M
T
Q
V
T
T
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
S854
S
M
R
P
T
L
C
S
R
I
P
Q
V
T
T
Dog
Lupus familis
XP_545861
952
103673
S854
S
M
R
P
S
L
C
S
R
I
P
E
V
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
S854
S
M
R
P
A
L
C
S
R
I
P
Q
V
T
T
Rat
Rattus norvegicus
Q32PZ3
944
103222
S854
S
M
R
P
S
L
C
S
R
I
P
Q
V
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
S829
A
A
Q
K
K
L
C
S
K
M
T
E
V
T
T
Frog
Xenopus laevis
NP_001087472
927
103492
H836
A
A
E
K
K
L
C
H
K
M
T
E
V
T
S
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
V842
A
A
Q
K
K
L
A
V
K
M
T
K
V
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
C837
T
S
V
S
V
K
C
C
E
K
I
L
A
I
A
Honey Bee
Apis mellifera
XP_396019
942
106098
C834
T
S
V
S
I
K
S
C
F
K
I
F
D
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
C832
L
S
S
H
E
E
V
C
D
K
I
F
K
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
L455
G
D
V
T
K
R
F
L
Q
D
N
N
L
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
40
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
40
26.6
20
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
60
100
100
N.A.
93.3
100
N.A.
N.A.
73.3
60
53.3
N.A.
13.3
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
31
0
0
8
0
8
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
70
24
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
8
0
0
8
8
8
% D
% Glu:
0
0
8
0
8
8
0
0
8
0
0
24
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
0
16
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
39
24
0
0
8
0
% I
% Lys:
0
0
0
31
39
16
0
0
31
24
0
8
8
0
8
% K
% Leu:
8
0
0
0
0
70
0
16
0
0
0
8
8
8
8
% L
% Met:
0
39
0
0
0
0
0
0
0
31
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
39
0
0
0
0
0
0
39
0
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
8
0
0
39
0
0
0
% Q
% Arg:
0
0
39
0
0
8
0
0
39
0
0
0
0
0
0
% R
% Ser:
39
24
8
16
16
0
8
47
0
0
0
0
0
8
8
% S
% Thr:
16
0
0
8
16
0
0
0
0
0
31
0
0
70
54
% T
% Val:
0
0
24
0
8
0
8
8
0
0
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _