KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
28.18
Human Site:
T336
Identified Species:
51.67
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
T336
K
D
P
N
N
S
L
T
L
W
V
I
D
Q
G
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
T320
A
I
H
D
N
S
R
T
I
Y
V
V
D
N
G
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
T336
K
D
P
N
N
S
L
T
L
W
V
I
D
Q
G
Dog
Lupus familis
XP_545861
952
103673
T336
K
D
P
N
N
N
L
T
L
W
V
I
D
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
T336
K
D
P
N
N
S
L
T
L
W
V
I
D
Q
G
Rat
Rattus norvegicus
Q32PZ3
944
103222
T336
K
D
P
N
N
S
L
T
L
W
V
I
D
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
T311
K
D
Q
D
N
S
R
T
T
F
V
I
D
N
G
Frog
Xenopus laevis
NP_001087472
927
103492
T317
K
N
K
D
N
S
K
T
L
F
V
V
D
V
G
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
C324
K
S
T
D
N
S
K
C
L
F
T
I
D
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
E328
E
W
A
E
R
L
V
E
I
R
G
L
C
R
L
Honey Bee
Apis mellifera
XP_396019
942
106098
E325
N
W
A
E
R
L
V
E
L
N
G
L
Q
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
L325
A
G
R
A
M
A
F
L
T
N
G
G
L
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
40
100
93.3
N.A.
100
100
N.A.
N.A.
60
53.3
46.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
73.3
80
60
N.A.
33.3
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
0
47
0
31
0
0
0
0
0
0
0
0
70
0
0
% D
% Glu:
8
0
0
16
0
0
0
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
24
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
24
8
0
0
70
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
0
8
0
0
0
0
0
0
16
0
0
54
0
0
0
% I
% Lys:
62
0
8
0
0
0
16
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
16
39
8
62
0
0
16
8
0
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
39
70
8
0
0
0
16
0
0
0
16
0
% N
% Pro:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
8
39
0
% Q
% Arg:
0
0
8
0
16
0
16
0
0
8
0
0
0
16
0
% R
% Ser:
0
8
0
0
0
62
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
62
16
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
16
0
0
0
62
16
0
8
0
% V
% Trp:
0
16
0
0
0
0
0
0
0
39
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _