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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
16.67
Human Site:
T921
Identified Species:
30.56
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
T921
K
G
D
H
S
P
V
T
R
A
A
A
A
C
L
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
K905
K
Q
E
P
D
E
K
K
A
E
V
V
Q
T
A
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
T921
K
G
D
Q
S
P
V
T
R
A
A
A
A
C
L
Dog
Lupus familis
XP_545861
952
103673
T921
K
G
K
E
S
P
V
T
R
A
A
A
A
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
T921
K
G
E
E
S
P
V
T
R
A
A
A
A
C
L
Rat
Rattus norvegicus
Q32PZ3
944
103222
T921
K
G
E
E
S
P
V
T
R
A
A
A
A
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
K896
K
Q
E
D
D
P
K
K
Q
H
I
I
N
A
A
Frog
Xenopus laevis
NP_001087472
927
103492
K903
K
Q
A
D
V
P
N
K
Q
H
I
I
N
V
A
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
K909
K
L
E
D
N
P
K
K
Q
N
A
I
D
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
A904
Q
L
P
D
D
T
R
A
K
A
R
E
V
A
T
Honey Bee
Apis mellifera
XP_396019
942
106098
K901
K
S
D
T
V
Q
D
K
K
I
K
E
L
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
K899
K
D
D
S
P
E
N
K
R
I
A
T
R
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
A518
P
N
I
V
T
F
S
A
V
P
H
P
D
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
13.3
13.3
20
N.A.
6.6
13.3
N.A.
26.6
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
26.6
20
40
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
16
8
47
54
39
39
39
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% C
% Asp:
0
8
31
31
24
0
8
0
0
0
0
0
16
0
0
% D
% Glu:
0
0
39
24
0
16
0
0
0
8
0
16
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
16
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
16
16
24
0
0
0
% I
% Lys:
85
0
8
0
0
0
24
47
16
0
8
0
0
0
8
% K
% Leu:
0
16
0
0
0
0
0
0
0
0
0
0
8
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
16
0
0
8
0
0
16
0
0
% N
% Pro:
8
0
8
8
8
62
0
0
0
8
0
8
0
0
0
% P
% Gln:
8
24
0
8
0
8
0
0
24
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
47
0
8
0
8
0
0
% R
% Ser:
0
8
0
8
39
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
8
8
0
39
0
0
0
8
0
8
8
% T
% Val:
0
0
0
8
16
0
39
0
8
0
8
8
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _