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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
32.42
Human Site:
Y486
Identified Species:
59.44
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
Y486
V
S
L
L
K
D
L
Y
K
C
S
E
K
D
S
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
Y470
V
S
L
L
K
Q
I
Y
K
T
T
K
N
E
K
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
Y486
V
S
L
L
K
D
L
Y
K
R
S
E
K
D
S
Dog
Lupus familis
XP_545861
952
103673
Y486
V
S
L
L
K
D
L
Y
K
R
S
E
K
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
Y486
V
S
L
L
K
D
L
Y
K
G
S
E
R
D
S
Rat
Rattus norvegicus
Q32PZ3
944
103222
Y486
V
A
L
L
K
D
L
Y
K
G
S
E
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
Y461
I
T
L
L
K
E
I
Y
K
K
T
K
N
E
K
Frog
Xenopus laevis
NP_001087472
927
103492
Y467
V
S
L
L
K
D
I
Y
K
K
T
K
N
E
K
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
Y474
V
S
L
L
K
E
M
Y
K
K
T
K
N
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
L475
G
V
D
I
L
K
R
L
Y
H
S
K
N
D
G
Honey Bee
Apis mellifera
XP_396019
942
106098
L472
G
V
N
I
L
K
K
L
Y
Q
S
K
D
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
L470
G
I
N
I
M
K
D
L
Y
K
S
P
N
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
T118
S
P
N
D
P
D
A
T
R
K
L
K
E
C
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
46.6
93.3
93.3
N.A.
86.6
80
N.A.
N.A.
33.3
53.3
46.6
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
73.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
80
N.A.
26.6
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
0
0
8
8
0
54
8
0
0
0
0
0
8
62
0
% D
% Glu:
0
0
0
0
0
16
0
0
0
0
0
39
8
31
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
0
0
0
0
0
16
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
8
0
24
0
0
24
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
70
24
8
0
70
39
0
54
24
0
31
% K
% Leu:
0
0
70
70
16
0
39
24
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
24
0
0
0
0
0
0
0
0
0
47
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
16
0
0
16
0
0
% R
% Ser:
8
54
0
0
0
0
0
0
0
0
62
0
0
0
47
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
31
0
0
0
0
% T
% Val:
62
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _