KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC45A
All Species:
21.82
Human Site:
Y602
Identified Species:
40
UniProt:
Q9H3U1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U1
NP_001034764.1
944
103077
Y602
N
C
T
N
S
Y
D
Y
E
E
P
D
P
K
M
Chimpanzee
Pan troglodytes
XP_001174363
929
103443
V586
N
C
T
N
S
Y
D
V
K
E
V
I
P
E
L
Rhesus Macaque
Macaca mulatta
XP_001092829
944
103078
Y602
N
C
T
N
S
Y
D
Y
E
E
P
D
P
K
M
Dog
Lupus familis
XP_545861
952
103673
Y602
N
C
T
N
S
Y
D
Y
E
E
P
D
P
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q99KD5
944
103429
Y602
N
C
T
N
S
Y
D
Y
E
E
P
D
P
K
M
Rat
Rattus norvegicus
Q32PZ3
944
103222
Y602
N
C
T
N
S
Y
D
Y
E
E
P
D
P
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415774
1004
111411
T577
N
C
T
N
S
Y
D
T
K
E
L
V
P
E
L
Frog
Xenopus laevis
NP_001087472
927
103492
V583
N
C
T
N
S
Y
D
V
K
E
V
I
P
E
M
Zebra Danio
Brachydanio rerio
NP_705959
934
103829
K590
N
C
T
N
S
Y
D
K
K
E
I
I
P
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524796
947
105029
K591
N
L
C
N
A
Y
E
K
Q
E
M
L
P
E
M
Honey Bee
Apis mellifera
XP_396019
942
106098
K588
N
L
C
N
A
Y
D
K
Q
E
L
I
P
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797752
921
101600
V586
N
L
T
N
C
Y
D
V
Q
K
P
E
P
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
I221
P
Q
Y
S
G
A
R
I
E
G
E
E
V
T
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.4
98.7
94
N.A.
94
94.3
N.A.
N.A.
52.1
55.6
54.7
N.A.
36.2
38.9
N.A.
43.7
Protein Similarity:
100
73
99.1
96.7
N.A.
97.1
97.4
N.A.
N.A.
69.6
75.6
74.5
N.A.
58.7
61.5
N.A.
66.7
P-Site Identity:
100
60
100
100
N.A.
100
100
N.A.
N.A.
60
66.6
66.6
N.A.
40
46.6
N.A.
46.6
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
80
80
80
N.A.
66.6
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
70
16
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
85
0
0
0
0
39
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
47
85
8
16
0
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
31
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
24
31
8
0
0
0
39
0
% K
% Leu:
0
24
0
0
0
0
0
0
0
0
16
8
0
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
70
% M
% Asn:
93
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
47
0
93
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
24
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
70
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
77
0
0
0
0
8
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
24
0
0
16
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
93
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _