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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMOC2
All Species:
18.79
Human Site:
S344
Identified Species:
41.33
UniProt:
Q9H3U7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U7
NP_071421.1
446
49674
S344
R
L
S
E
P
D
P
S
H
T
L
E
E
R
V
Chimpanzee
Pan troglodytes
XP_530989
545
60408
S443
R
L
S
E
P
D
P
S
H
T
L
E
E
R
V
Rhesus Macaque
Macaca mulatta
XP_001110441
489
54123
I394
T
T
D
M
V
Q
A
I
N
S
A
A
P
T
G
Dog
Lupus familis
XP_863173
445
49539
S343
R
L
S
E
P
D
P
S
H
T
L
E
E
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CD91
447
49873
S344
R
L
S
E
P
D
P
S
H
T
L
E
E
R
V
Rat
Rattus norvegicus
NP_001099685
447
49901
S344
R
L
S
E
P
D
P
S
H
T
L
E
E
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419600
457
50926
N352
R
V
S
E
P
D
P
N
H
T
L
E
E
R
V
Frog
Xenopus laevis
NP_001137372
463
51067
N366
R
F
S
E
P
D
P
N
H
T
L
E
E
R
V
Zebra Danio
Brachydanio rerio
Q9YHV4
322
35499
L229
H
L
R
R
A
T
C
L
L
G
R
S
I
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097254
520
59095
T417
S
N
S
S
M
W
K
T
D
D
E
R
I
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793433
569
64022
D439
R
V
F
V
D
C
P
D
D
K
K
K
R
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
52.1
94.3
N.A.
94.6
95
N.A.
N.A.
87.5
52.2
20.1
N.A.
21.7
N.A.
N.A.
21
Protein Similarity:
100
80.5
66.2
96.6
N.A.
97.3
97.3
N.A.
N.A.
91.9
66.3
31.6
N.A.
39.4
N.A.
N.A.
38.6
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
100
93.3
13.3
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
64
0
10
19
10
0
0
0
0
0
% D
% Glu:
0
0
0
64
0
0
0
0
0
0
10
64
64
0
0
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% G
% His:
10
0
0
0
0
0
0
0
64
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
19
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
10
10
0
0
0
% K
% Leu:
0
55
0
0
0
0
0
10
10
0
64
0
0
0
10
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
19
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
64
0
73
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
73
0
10
10
0
0
0
0
0
0
10
10
10
64
0
% R
% Ser:
10
0
73
10
0
0
0
46
0
10
0
10
0
0
0
% S
% Thr:
10
10
0
0
0
10
0
10
0
64
0
0
0
10
10
% T
% Val:
0
19
0
10
10
0
0
0
0
0
0
0
0
0
73
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _