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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMOC2
All Species:
29.09
Human Site:
S405
Identified Species:
64
UniProt:
Q9H3U7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U7
NP_071421.1
446
49674
S405
V
N
N
D
K
S
I
S
V
Q
E
L
M
G
C
Chimpanzee
Pan troglodytes
XP_530989
545
60408
S504
V
N
N
D
K
S
I
S
V
Q
E
L
M
G
C
Rhesus Macaque
Macaca mulatta
XP_001110441
489
54123
P452
Y
V
K
K
K
A
K
P
K
K
C
A
R
R
F
Dog
Lupus familis
XP_863173
445
49539
S404
V
N
N
D
K
S
I
S
V
Q
E
L
M
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CD91
447
49873
T405
M
N
N
D
K
S
I
T
V
Q
E
L
M
G
C
Rat
Rattus norvegicus
NP_001099685
447
49901
T405
M
N
N
D
K
S
I
T
V
Q
E
L
M
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419600
457
50926
S413
V
N
N
D
K
S
L
S
V
Q
E
L
M
G
C
Frog
Xenopus laevis
NP_001137372
463
51067
S427
L
N
K
D
K
S
I
S
F
P
E
L
K
G
C
Zebra Danio
Brachydanio rerio
Q9YHV4
322
35499
V286
E
S
R
S
E
E
A
V
C
A
S
D
N
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097254
520
59095
S476
V
N
G
D
K
K
I
S
L
A
E
W
L
N
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793433
569
64022
A501
N
G
N
N
Y
L
E
A
K
E
T
A
T
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
52.1
94.3
N.A.
94.6
95
N.A.
N.A.
87.5
52.2
20.1
N.A.
21.7
N.A.
N.A.
21
Protein Similarity:
100
80.5
66.2
96.6
N.A.
97.3
97.3
N.A.
N.A.
91.9
66.3
31.6
N.A.
39.4
N.A.
N.A.
38.6
P-Site Identity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
66.6
0
N.A.
53.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
100
73.3
13.3
N.A.
66.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
19
0
19
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
73
% C
% Asp:
0
0
0
73
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
0
10
10
10
0
0
10
73
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
0
0
0
64
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
10
82
10
10
0
19
10
0
0
10
0
0
% K
% Leu:
10
0
0
0
0
10
10
0
10
0
0
64
10
0
0
% L
% Met:
19
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% M
% Asn:
10
73
64
10
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
10
0
10
0
64
0
55
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
19
0
0
10
0
10
10
10
% T
% Val:
46
10
0
0
0
0
0
10
55
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _