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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMOC2 All Species: 27.58
Human Site: T346 Identified Species: 60.67
UniProt: Q9H3U7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3U7 NP_071421.1 446 49674 T346 S E P D P S H T L E E R V V H
Chimpanzee Pan troglodytes XP_530989 545 60408 T445 S E P D P S H T L E E R V V H
Rhesus Macaque Macaca mulatta XP_001110441 489 54123 S396 D M V Q A I N S A A P T G G G
Dog Lupus familis XP_863173 445 49539 T345 S E P D P S H T L E E R V V H
Cat Felis silvestris
Mouse Mus musculus Q8CD91 447 49873 T346 S E P D P S H T L E E R V V H
Rat Rattus norvegicus NP_001099685 447 49901 T346 S E P D P S H T L E E R V V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419600 457 50926 T354 S E P D P N H T L E E R V V H
Frog Xenopus laevis NP_001137372 463 51067 T368 S E P D P N H T L E E R V V L
Zebra Danio Brachydanio rerio Q9YHV4 322 35499 G231 R R A T C L L G R S I G V A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097254 520 59095 D419 S S M W K T D D E R I A T L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793433 569 64022 K441 F V D C P D D K K K R F L I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 52.1 94.3 N.A. 94.6 95 N.A. N.A. 87.5 52.2 20.1 N.A. 21.7 N.A. N.A. 21
Protein Similarity: 100 80.5 66.2 96.6 N.A. 97.3 97.3 N.A. N.A. 91.9 66.3 31.6 N.A. 39.4 N.A. N.A. 38.6
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. N.A. 93.3 86.6 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. 100 93.3 13.3 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 10 10 0 10 0 10 0 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 64 0 10 19 10 0 0 0 0 0 0 0 % D
% Glu: 0 64 0 0 0 0 0 0 10 64 64 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 10 10 10 10 % G
% His: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 55 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 19 0 0 10 0 % I
% Lys: 0 0 0 0 10 0 0 10 10 10 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 10 10 0 64 0 0 0 10 10 10 % L
% Met: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 19 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 0 73 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 0 0 0 0 0 0 10 10 10 64 0 0 0 % R
% Ser: 73 10 0 0 0 46 0 10 0 10 0 0 0 0 10 % S
% Thr: 0 0 0 10 0 10 0 64 0 0 0 10 10 0 0 % T
% Val: 0 10 10 0 0 0 0 0 0 0 0 0 73 64 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _