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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMOC2
All Species:
21.82
Human Site:
Y296
Identified Species:
48
UniProt:
Q9H3U7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3U7
NP_071421.1
446
49674
Y296
P
A
K
A
R
D
L
Y
K
G
R
Q
L
Q
G
Chimpanzee
Pan troglodytes
XP_530989
545
60408
Y395
P
A
K
A
R
D
L
Y
K
G
R
Q
L
Q
G
Rhesus Macaque
Macaca mulatta
XP_001110441
489
54123
S349
Y
V
M
P
S
C
E
S
D
A
R
A
K
S
T
Dog
Lupus familis
XP_863173
445
49539
Y296
P
T
K
T
R
D
L
Y
K
G
R
Q
L
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CD91
447
49873
Y296
P
A
K
A
R
D
L
Y
K
N
R
P
L
Q
G
Rat
Rattus norvegicus
NP_001099685
447
49901
Y296
P
A
K
A
R
D
L
Y
K
N
R
P
L
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419600
457
50926
Y304
P
T
K
T
K
D
L
Y
K
G
R
Q
L
Q
G
Frog
Xenopus laevis
NP_001137372
463
51067
F317
N
T
D
A
E
D
P
F
K
D
R
E
L
A
G
Zebra Danio
Brachydanio rerio
Q9YHV4
322
35499
V184
P
G
S
S
T
C
V
V
D
Q
T
N
N
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097254
520
59095
T310
C
W
M
D
Q
S
V
T
L
E
E
Q
G
H
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793433
569
64022
E356
P
V
L
S
C
E
T
E
R
L
R
A
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
52.1
94.3
N.A.
94.6
95
N.A.
N.A.
87.5
52.2
20.1
N.A.
21.7
N.A.
N.A.
21
Protein Similarity:
100
80.5
66.2
96.6
N.A.
97.3
97.3
N.A.
N.A.
91.9
66.3
31.6
N.A.
39.4
N.A.
N.A.
38.6
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
40
6.6
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
53.3
20
N.A.
26.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
46
0
0
0
0
0
10
0
19
0
19
0
% A
% Cys:
10
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
64
0
0
19
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
10
10
0
10
10
10
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
37
0
0
10
0
73
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
55
0
10
0
0
0
64
0
0
0
10
0
0
% K
% Leu:
0
0
10
0
0
0
55
0
10
10
0
0
73
0
0
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
19
0
10
10
0
0
% N
% Pro:
73
0
0
10
0
0
10
0
0
0
0
19
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
46
0
55
0
% Q
% Arg:
0
0
0
0
46
0
0
0
10
0
82
0
0
0
0
% R
% Ser:
0
0
10
19
10
10
0
10
0
0
0
0
0
10
0
% S
% Thr:
0
28
0
19
10
0
10
10
0
0
10
0
0
0
10
% T
% Val:
0
19
0
0
0
0
19
10
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
55
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _