KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRMS
All Species:
29.39
Human Site:
S381
Identified Species:
58.79
UniProt:
Q9H3Y6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3Y6
NP_543013.1
488
54507
S381
L
L
K
D
D
I
Y
S
P
S
S
S
S
K
I
Chimpanzee
Pan troglodytes
XP_525384
492
54970
S381
L
L
K
D
D
I
Y
S
P
S
S
S
S
K
I
Rhesus Macaque
Macaca mulatta
XP_001114037
492
54778
S381
L
L
K
D
D
I
Y
S
P
S
S
G
S
K
I
Dog
Lupus familis
XP_534478
629
68321
S518
L
L
K
E
D
I
Y
S
P
S
S
G
C
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62270
496
55740
S385
L
L
K
D
D
V
Y
S
P
S
S
G
S
K
I
Rat
Rattus norvegicus
Q62662
506
58147
E389
V
D
N
E
D
I
Y
E
S
K
H
E
I
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506797
498
57086
S387
L
L
K
D
D
I
Y
S
T
S
S
S
T
K
I
Chicken
Gallus gallus
P42683
508
58121
T394
L
I
E
D
N
E
Y
T
A
R
E
G
A
K
F
Frog
Xenopus laevis
P13116
532
59718
T416
L
I
E
D
N
E
Y
T
A
R
Q
G
A
K
F
Zebra Danio
Brachydanio rerio
XP_698462
1009
113199
T895
I
I
E
D
N
E
Y
T
A
R
E
G
A
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
E401
L
I
K
E
D
E
Y
E
A
R
V
G
A
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
E413
V
I
K
D
E
I
Y
E
S
H
V
G
A
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.3
59.9
N.A.
77.8
41.2
N.A.
68.6
40.7
39.6
23.4
N.A.
41.9
N.A.
N.A.
42.4
Protein Similarity:
100
99.1
95.9
65.9
N.A.
85
55.5
N.A.
81.5
56.8
53.9
33.5
N.A.
57.6
N.A.
N.A.
57.9
P-Site Identity:
100
100
93.3
80
N.A.
86.6
26.6
N.A.
86.6
26.6
26.6
20
N.A.
26.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
46.6
N.A.
93.3
60
60
60
N.A.
53.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
34
0
0
0
42
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
75
67
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
25
9
34
0
25
0
0
17
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
9
42
0
0
0
59
0
0
0
0
0
0
9
0
50
% I
% Lys:
0
0
67
0
0
0
0
0
0
9
0
0
0
92
0
% K
% Leu:
75
50
0
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
25
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
34
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
50
17
50
50
25
34
0
0
% S
% Thr:
0
0
0
0
0
0
0
25
9
0
0
0
9
0
0
% T
% Val:
17
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _