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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C20orf135
All Species:
27.58
Human Site:
S431
Identified Species:
50.56
UniProt:
Q9H3Z7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3Z7
NP_542189.1
469
52555
S431
W
L
V
G
Q
G
L
S
S
R
R
R
R
R
L
Chimpanzee
Pan troglodytes
XP_525389
469
52510
S431
W
L
V
G
Q
G
L
S
S
R
R
R
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001084135
469
52012
S431
W
L
V
G
Q
G
L
S
S
R
R
R
R
R
L
Dog
Lupus familis
XP_859552
431
48988
N393
W
S
V
G
E
D
M
N
A
D
G
R
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80YU0
474
53279
S436
W
F
V
G
Q
G
L
S
A
R
R
R
R
Q
L
Rat
Rattus norvegicus
Q5XIL6
474
53276
S436
W
F
V
G
Q
G
L
S
A
R
R
R
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508067
468
52322
P418
W
S
V
G
V
T
L
P
P
K
K
R
R
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080653
554
62865
S516
W
S
V
G
E
D
M
S
S
E
G
R
K
Q
L
Zebra Danio
Brachydanio rerio
NP_001104648
543
61694
T505
W
S
V
G
E
D
M
T
L
E
G
R
R
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647880
524
58384
R494
F
L
L
R
K
H
L
R
D
Y
N
S
T
H
C
Honey Bee
Apis mellifera
XP_395377
505
56966
D459
S
M
L
G
Q
D
C
D
S
K
I
K
Q
Q
I
Nematode Worm
Caenorhab. elegans
P41879
482
54732
S443
G
V
S
L
R
E
E
S
T
Q
R
K
R
L
F
Sea Urchin
Strong. purpuratus
XP_786661
511
57178
T485
Y
L
S
T
K
Y
M
T
D
F
D
S
T
H
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.3
53.9
N.A.
84.1
83.7
N.A.
70.5
N.A.
47.2
46
N.A.
30.9
35.6
31.3
35.4
Protein Similarity:
100
98.9
96.1
71
N.A.
89.8
89
N.A.
78.4
N.A.
63
62.9
N.A.
49.2
53.4
52.9
54.7
P-Site Identity:
100
100
100
33.3
N.A.
80
80
N.A.
46.6
N.A.
46.6
40
N.A.
13.3
20
20
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
86.6
N.A.
66.6
N.A.
73.3
66.6
N.A.
33.3
66.6
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
0
0
0
31
0
8
16
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
24
8
8
0
0
16
0
0
0
0
0
% E
% Phe:
8
16
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
8
0
0
77
0
39
0
0
0
0
24
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
24
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
16
0
0
0
0
16
8
16
8
0
0
% K
% Leu:
0
39
16
8
0
0
54
0
8
0
0
0
0
8
70
% L
% Met:
0
8
0
0
0
0
31
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
47
0
0
0
0
8
0
0
16
47
0
% Q
% Arg:
0
0
0
8
8
0
0
8
0
39
47
70
62
24
0
% R
% Ser:
8
31
16
0
0
0
0
54
39
0
0
16
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
16
8
0
0
0
16
0
0
% T
% Val:
0
8
70
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _