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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSN1 All Species: 17.27
Human Site: S121 Identified Species: 54.29
UniProt: Q9H410 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H410 NP_001138787.1 356 40067 S121 H Q G I T E L S R S I S V D L
Chimpanzee Pan troglodytes XP_514622 399 44351 S164 S E I I D E L S R S I S V D L
Rhesus Macaque Macaca mulatta XP_001094009 354 40066 S121 H Q G I T E L S R S I S V D L
Dog Lupus familis XP_852834 354 40008 S121 H Q G I T E L S R S I S A N L
Cat Felis silvestris
Mouse Mus musculus Q9CYC5 348 39534 C119 H P G I T E L C R S I S V K L
Rat Rattus norvegicus NP_001020939 348 39677 S119 H P G I T E L S R S I S M K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001038125 349 38599 T120 P P F H E D V T A L S Q A I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923648 330 36657 A101 R G R R S L P A F S S S S Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 94.3 79.4 N.A. 70.2 69.9 N.A. N.A. 38.7 N.A. 24.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71.4 96.6 86.5 N.A. 79.2 78.9 N.A. N.A. 55.6 N.A. 44.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 100 86.6 N.A. 80 80 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 100 93.3 N.A. 80 86.6 N.A. N.A. 20 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 13 0 0 0 25 0 0 % A
% Cys: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 13 0 0 0 0 0 0 0 38 0 % D
% Glu: 0 13 0 0 13 75 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 13 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 0 13 63 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 63 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 75 0 0 0 0 0 0 75 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % K
% Leu: 0 0 0 0 0 13 75 0 0 13 0 0 0 0 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 13 38 0 0 0 0 13 0 0 0 0 0 0 0 13 % P
% Gln: 0 38 0 0 0 0 0 0 0 0 0 13 0 13 0 % Q
% Arg: 13 0 13 13 0 0 0 0 75 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 13 0 0 63 0 88 25 88 13 0 13 % S
% Thr: 0 0 0 0 63 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 13 0 0 0 0 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _