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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIPK3 All Species: 16.67
Human Site: S982 Identified Species: 40.74
UniProt: Q9H422 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H422 NP_001041665.1 1215 133743 S982 E N T E L V S S A D T E T K P
Chimpanzee Pan troglodytes XP_001144457 1215 133742 S982 E N T E L V S S A D T E T K P
Rhesus Macaque Macaca mulatta XP_001083121 1215 133605 S982 E N T E L L S S A D T E T K P
Dog Lupus familis XP_533158 1215 133696 S982 Q N T E L V T S A N T E T K P
Cat Felis silvestris
Mouse Mus musculus Q9ERH7 1192 130104 A967 A G P E A K P A V G T A V E P
Rat Rattus norvegicus O88850 1191 129726 A966 A G T E A K P A L S T A V E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506961 1214 132769 S980 P N G D S L A S A D Q E A K P
Chicken Gallus gallus XP_419634 1193 130795 A968 V N S E T K S A V C T V V V P
Frog Xenopus laevis Q2TAE3 750 84138 R528 S D P T H Q H R H S G G H F T
Zebra Danio Brachydanio rerio NP_001073628 1261 137174 A1024 D N N Q N C K A T G S T E T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.8 95.4 N.A. 88.9 88.8 N.A. 84.8 80.3 22.9 61.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 98.5 97.8 N.A. 93 92.5 N.A. 90.2 86.6 34.4 74 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 20 26.6 N.A. 46.6 33.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 33.3 40 N.A. 66.6 46.6 6.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 20 0 10 40 50 0 0 20 10 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % C
% Asp: 10 10 0 10 0 0 0 0 0 40 0 0 0 0 0 % D
% Glu: 30 0 0 70 0 0 0 0 0 0 0 50 10 20 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 20 10 0 0 0 0 0 0 20 10 10 0 0 0 % G
% His: 0 0 0 0 10 0 10 0 10 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 30 10 0 0 0 0 0 0 50 0 % K
% Leu: 0 0 0 0 40 20 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 70 10 0 10 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 20 0 0 0 20 0 0 0 0 0 0 0 80 % P
% Gln: 10 0 0 10 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 10 0 40 50 0 20 10 0 0 0 0 % S
% Thr: 0 0 50 10 10 0 10 0 10 0 70 10 40 10 10 % T
% Val: 10 0 0 0 0 30 0 0 20 0 0 10 30 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _