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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIPK3
All Species:
20.3
Human Site:
T43
Identified Species:
49.63
UniProt:
Q9H422
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H422
NP_001041665.1
1215
133743
T43
Q
E
R
N
Y
P
R
T
Y
V
N
G
R
N
F
Chimpanzee
Pan troglodytes
XP_001144457
1215
133742
T43
Q
E
R
N
Y
P
R
T
Y
V
N
G
R
N
F
Rhesus Macaque
Macaca mulatta
XP_001083121
1215
133605
T43
Q
E
R
N
Y
P
R
T
Y
V
N
G
R
N
F
Dog
Lupus familis
XP_533158
1215
133696
T43
Q
E
R
N
Y
P
R
T
Y
V
N
G
K
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERH7
1192
130104
I43
Q
E
R
T
Y
P
Q
I
H
V
N
G
R
N
F
Rat
Rattus norvegicus
O88850
1191
129726
I43
Q
E
R
A
C
P
Q
I
H
V
N
G
R
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506961
1214
132769
T43
H
E
R
T
Y
P
R
T
C
V
N
G
R
N
F
Chicken
Gallus gallus
XP_419634
1193
130795
I43
H
E
R
A
Y
P
Q
I
Y
V
N
G
K
N
F
Frog
Xenopus laevis
Q2TAE3
750
84138
Zebra Danio
Brachydanio rerio
NP_001073628
1261
137174
T43
H
E
R
A
Y
P
Q
T
Y
L
N
G
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
95.4
N.A.
88.9
88.8
N.A.
84.8
80.3
22.9
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.5
97.8
N.A.
93
92.5
N.A.
90.2
86.6
34.4
74
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
60
N.A.
80
66.6
0
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
80
80
0
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% G
% His:
30
0
0
0
0
0
0
0
20
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
0
0
0
0
0
0
90
0
0
70
0
% N
% Pro:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% P
% Gln:
60
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
90
0
0
0
50
0
0
0
0
0
70
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
20
0
0
0
60
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
80
0
0
0
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _