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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK15
All Species:
6.36
Human Site:
S271
Identified Species:
12.73
UniProt:
Q9H427
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H427
NP_071753.1
330
36130
S271
R
P
P
G
A
P
E
S
R
G
L
W
L
P
R
Chimpanzee
Pan troglodytes
XP_001152552
330
36183
S271
C
R
P
G
A
P
E
S
R
G
L
W
L
P
H
Rhesus Macaque
Macaca mulatta
XP_001099894
470
51850
M367
L
A
G
N
R
N
S
M
V
I
H
I
P
E
E
Dog
Lupus familis
XP_543011
331
35891
S271
L
R
A
G
A
P
E
S
R
G
R
S
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3LS21
402
44892
R270
I
L
A
G
N
P
R
R
V
S
V
R
A
P
Q
Rat
Rattus norvegicus
Q8R5I0
318
35633
R259
A
P
E
R
A
A
L
R
R
A
S
V
F
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513444
490
53222
R391
A
G
V
G
R
D
P
R
R
G
R
P
P
R
F
Chicken
Gallus gallus
XP_417369
371
41583
L271
L
R
R
A
R
N
A
L
I
P
L
V
Q
E
D
Frog
Xenopus laevis
Q63ZI0
374
42700
M271
L
A
G
N
R
N
S
M
I
I
H
I
Q
E
D
Zebra Danio
Brachydanio rerio
NP_001104701
300
33990
P245
F
L
N
L
V
L
Q
P
R
T
P
G
S
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394509
367
40863
L271
A
A
Q
G
A
V
R
L
E
G
D
V
I
T
A
Nematode Worm
Caenorhab. elegans
O17185
329
36973
V270
A
A
Q
G
L
V
R
V
G
D
P
T
A
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
44.6
83.3
N.A.
49.2
76.6
N.A.
42.2
60.3
53.2
54.8
N.A.
N.A.
41.4
43.9
N.A.
Protein Similarity:
100
96.6
51.9
86.4
N.A.
57.4
80.9
N.A.
48.7
68.7
63.9
65.1
N.A.
N.A.
56.1
58.7
N.A.
P-Site Identity:
100
80
0
60
N.A.
20
26.6
N.A.
20
6.6
0
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
100
80
0
60
N.A.
33.3
26.6
N.A.
20
6.6
0
13.3
N.A.
N.A.
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
34
17
9
42
9
9
0
0
9
0
0
17
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
9
9
0
0
9
25
% D
% Glu:
0
0
9
0
0
0
25
0
9
0
0
0
0
25
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
9
17
59
0
0
0
0
9
42
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
17
0
0
9
9
% H
% Ile:
9
0
0
0
0
0
0
0
17
17
0
17
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
34
17
0
9
9
9
9
17
0
0
25
0
17
0
9
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
17
9
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
17
0
0
34
9
9
0
9
17
9
25
34
0
% P
% Gln:
0
0
17
0
0
0
9
0
0
0
0
0
17
0
9
% Q
% Arg:
9
25
9
9
34
0
25
25
50
0
17
9
0
17
25
% R
% Ser:
0
0
0
0
0
0
17
25
0
9
9
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% T
% Val:
0
0
9
0
9
17
0
9
17
0
9
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _