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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4B
All Species:
22.42
Human Site:
S37
Identified Species:
35.24
UniProt:
Q9H444
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H444
NP_789782.1
224
24950
S37
R
D
T
E
E
M
L
S
K
K
Q
E
F
L
E
Chimpanzee
Pan troglodytes
XP_528179
346
37934
G150
R
E
T
E
E
M
L
G
K
K
Q
E
Y
L
E
Rhesus Macaque
Macaca mulatta
XP_001105255
224
24948
S37
R
D
T
E
E
M
L
S
K
K
Q
E
Y
L
E
Dog
Lupus familis
XP_542966
224
24965
S37
R
D
T
E
E
M
L
S
K
K
Q
E
F
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8B3
224
24918
S37
R
D
T
E
E
M
L
S
K
K
Q
E
F
L
E
Rat
Rattus norvegicus
Q569C1
232
26305
A37
R
E
I
E
E
M
M
A
K
K
Q
E
Y
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518785
217
23847
K39
D
V
A
E
R
T
I
K
R
P
R
R
G
G
C
Chicken
Gallus gallus
Q5ZHP5
227
25137
S39
R
D
T
E
E
M
L
S
K
K
Q
E
F
L
E
Frog
Xenopus laevis
Q5XGW6
222
24831
A35
R
D
T
E
E
M
L
A
K
K
Q
E
F
L
E
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
A35
R
E
T
E
E
M
L
A
K
K
Q
D
F
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI9
226
25133
L38
I
E
E
K
I
S
N
L
E
A
E
L
R
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495337
221
24666
E34
R
E
T
E
E
M
L
E
K
K
Q
E
F
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82197
213
23996
T42
N
V
L
L
K
K
A
T
G
E
V
E
K
A
K
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
S34
R
E
H
I
N
L
L
S
K
K
Q
S
H
L
R
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
Q36
R
T
Q
L
D
M
L
Q
K
R
E
R
H
L
Q
Conservation
Percent
Protein Identity:
100
43.9
99.5
97.7
N.A.
99.5
59.4
N.A.
76.7
91.6
87
83.9
N.A.
26.1
N.A.
62
N.A.
Protein Similarity:
100
56.3
100
98.6
N.A.
100
76.7
N.A.
81.6
95.5
93.7
92.4
N.A.
48.2
N.A.
77.6
N.A.
P-Site Identity:
100
80
93.3
100
N.A.
100
66.6
N.A.
6.6
100
93.3
80
N.A.
0
N.A.
86.6
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
26.6
100
100
100
N.A.
26.6
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.3
40.8
38.1
Protein Similarity:
N.A.
N.A.
N.A.
55.3
56.2
59.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
46.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
20
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
7
40
0
0
7
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
40
7
74
67
0
0
7
7
7
14
67
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
7
7
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
14
0
0
% H
% Ile:
7
0
7
7
7
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
7
7
0
7
80
74
0
0
7
7
7
% K
% Leu:
0
0
7
14
0
7
74
7
0
0
0
7
0
80
0
% L
% Met:
0
0
0
0
0
74
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
7
0
0
74
0
0
0
7
% Q
% Arg:
80
0
0
0
7
0
0
0
7
7
7
14
7
0
7
% R
% Ser:
0
0
0
0
0
7
0
40
0
0
0
7
0
0
0
% S
% Thr:
0
7
60
0
0
7
0
7
0
0
0
0
0
0
0
% T
% Val:
0
14
0
0
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _