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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4B
All Species:
25.76
Human Site:
T147
Identified Species:
40.48
UniProt:
Q9H444
Number Species:
14
Phosphosite Substitution
Charge Score:
0.57
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H444
NP_789782.1
224
24950
T147
E
L
A
E
E
I
S
T
A
I
S
K
P
V
G
Chimpanzee
Pan troglodytes
XP_528179
346
37934
E260
D
I
A
Q
E
I
S
E
A
F
S
Q
R
V
G
Rhesus Macaque
Macaca mulatta
XP_001105255
224
24948
T147
E
L
A
E
E
I
S
T
A
I
S
K
P
V
G
Dog
Lupus familis
XP_542966
224
24965
T147
E
L
A
E
E
I
S
T
A
I
S
K
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8B3
224
24918
T147
E
L
A
E
E
I
S
T
A
I
S
K
P
V
G
Rat
Rattus norvegicus
Q569C1
232
26305
E147
D
I
A
Q
E
I
S
E
A
F
S
Q
R
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518785
217
23847
T139
E
L
A
D
E
I
S
T
A
I
S
K
P
V
G
Chicken
Gallus gallus
Q5ZHP5
227
25137
T149
E
L
A
D
E
I
S
T
A
I
S
K
P
V
G
Frog
Xenopus laevis
Q5XGW6
222
24831
D145
E
L
A
Q
E
I
S
D
A
I
S
K
P
V
G
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
D145
E
L
A
Q
E
I
S
D
A
I
S
R
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI9
226
25133
E147
E
Q
A
D
E
V
Q
E
A
L
G
R
T
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495337
221
24666
E144
E
V
A
N
E
I
A
E
A
I
S
N
P
V
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82197
213
23996
E142
E
N
M
K
Q
I
Q
E
A
L
S
A
P
F
G
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
D145
E
L
G
D
E
I
S
D
A
I
S
R
P
L
I
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
T146
D
L
S
N
E
I
A
T
A
I
T
S
A
N
I
Conservation
Percent
Protein Identity:
100
43.9
99.5
97.7
N.A.
99.5
59.4
N.A.
76.7
91.6
87
83.9
N.A.
26.1
N.A.
62
N.A.
Protein Similarity:
100
56.3
100
98.6
N.A.
100
76.7
N.A.
81.6
95.5
93.7
92.4
N.A.
48.2
N.A.
77.6
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
46.6
N.A.
93.3
93.3
86.6
80
N.A.
33.3
N.A.
66.6
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
73.3
N.A.
100
100
93.3
93.3
N.A.
60
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.3
40.8
38.1
Protein Similarity:
N.A.
N.A.
N.A.
55.3
56.2
59.2
P-Site Identity:
N.A.
N.A.
N.A.
40
60
40
P-Site Similarity:
N.A.
N.A.
N.A.
60
80
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
0
14
0
100
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
27
0
0
0
20
0
0
0
0
0
0
0
% D
% Glu:
80
0
0
27
94
0
0
34
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
14
0
0
0
7
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
94
0
0
0
74
0
0
0
0
14
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
47
0
0
0
% K
% Leu:
0
67
0
0
0
0
0
0
0
14
0
0
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
14
0
0
0
0
0
0
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
74
0
0
% P
% Gln:
0
7
0
27
7
0
14
0
0
0
0
14
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
20
14
0
0
% R
% Ser:
0
0
7
0
0
0
74
0
0
0
87
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
47
0
0
7
0
7
0
0
% T
% Val:
0
7
0
0
0
7
0
0
0
0
0
0
0
74
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _