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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4B
All Species:
30.61
Human Site:
T188
Identified Species:
48.1
UniProt:
Q9H444
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H444
NP_789782.1
224
24950
T188
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Chimpanzee
Pan troglodytes
XP_528179
346
37934
N295
E
L
N
K
K
M
T
N
I
R
L
P
N
V
P
Rhesus Macaque
Macaca mulatta
XP_001105255
224
24948
T188
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Dog
Lupus familis
XP_542966
224
24965
T188
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8B3
224
24918
T188
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Rat
Rattus norvegicus
Q569C1
232
26305
S182
E
L
N
K
K
M
T
S
M
E
L
P
N
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518785
217
23847
T180
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Chicken
Gallus gallus
Q5ZHP5
227
25137
T190
L
E
I
S
G
P
E
T
V
P
L
P
N
V
P
Frog
Xenopus laevis
Q5XGW6
222
24831
T186
L
E
V
Q
G
P
E
T
V
P
L
P
N
V
P
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
D186
L
Q
I
S
G
P
E
D
V
P
L
P
N
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI9
226
25133
E191
D
D
V
V
K
A
P
E
A
P
S
R
E
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495337
221
24666
P184
L
L
D
A
R
A
P
P
V
T
L
P
D
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82197
213
23996
P177
L
E
E
Q
L
L
Q
P
V
P
I
H
V
P
Q
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
N188
K
I
V
N
N
N
V
N
A
A
P
I
S
E
N
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
S184
K
L
H
E
T
G
G
S
I
P
V
H
D
K
I
Conservation
Percent
Protein Identity:
100
43.9
99.5
97.7
N.A.
99.5
59.4
N.A.
76.7
91.6
87
83.9
N.A.
26.1
N.A.
62
N.A.
Protein Similarity:
100
56.3
100
98.6
N.A.
100
76.7
N.A.
81.6
95.5
93.7
92.4
N.A.
48.2
N.A.
77.6
N.A.
P-Site Identity:
100
33.3
100
100
N.A.
100
33.3
N.A.
100
100
86.6
86.6
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
46.6
N.A.
100
100
93.3
93.3
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.3
40.8
38.1
Protein Similarity:
N.A.
N.A.
N.A.
55.3
56.2
59.2
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
14
0
0
14
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
0
0
7
0
0
0
0
14
0
0
% D
% Glu:
14
54
7
7
0
0
54
7
0
7
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
54
7
7
0
0
0
0
0
0
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
7
47
0
0
0
0
0
14
0
7
7
0
0
7
% I
% Lys:
14
0
0
14
20
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
67
27
0
0
7
7
0
0
0
0
74
0
0
0
0
% L
% Met:
0
0
0
0
0
14
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
14
7
7
7
0
14
0
0
0
0
67
0
7
% N
% Pro:
0
0
0
0
0
54
14
14
0
74
7
74
0
14
74
% P
% Gln:
0
7
0
14
0
0
7
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
7
0
0
0
0
7
0
7
0
0
0
% R
% Ser:
0
0
0
47
0
0
0
14
0
0
7
0
7
0
0
% S
% Thr:
0
0
0
0
7
0
14
47
0
7
0
0
0
7
0
% T
% Val:
0
0
20
7
0
0
7
0
67
0
7
0
7
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _