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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD8
All Species:
14.85
Human Site:
T157
Identified Species:
29.7
UniProt:
Q9H461
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H461
NP_114072.1
694
73300
T157
D
Y
N
R
T
D
L
T
T
A
A
P
S
P
P
Chimpanzee
Pan troglodytes
XP_001142144
668
70462
G181
G
G
G
R
G
G
G
G
G
D
A
A
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001096837
635
68033
T157
D
Y
N
R
T
D
L
T
T
A
A
P
S
P
P
Dog
Lupus familis
XP_545614
589
64543
L139
S
C
D
R
L
P
V
L
G
R
D
A
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61091
685
73197
T157
D
Y
N
R
T
D
L
T
T
A
A
P
S
P
P
Rat
Rattus norvegicus
Q498S8
684
72990
T157
D
Y
N
R
T
D
L
T
T
A
A
P
S
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA06
523
59263
Q72
P
V
C
T
V
L
E
Q
A
I
P
P
C
R
S
Frog
Xenopus laevis
O93274
581
65360
L131
D
R
M
R
C
D
R
L
P
E
Q
G
N
P
D
Zebra Danio
Brachydanio rerio
NP_570993
579
65231
R129
F
P
W
P
D
R
M
R
C
D
L
L
P
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
A186
E
Q
P
S
Y
T
E
A
G
S
G
G
S
S
G
Honey Bee
Apis mellifera
XP_397259
711
74000
S220
E
Q
D
N
H
T
S
S
T
G
H
G
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188449
555
62346
K105
I
C
L
A
D
Y
H
K
P
L
M
A
C
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
86.3
59.7
N.A.
95.5
95.8
N.A.
N.A.
40.6
70.6
71
N.A.
50.4
47.5
N.A.
53.4
Protein Similarity:
100
96.1
88.1
67.4
N.A.
95.9
96.2
N.A.
N.A.
52.5
75.6
76.5
N.A.
60.8
58.2
N.A.
63.2
P-Site Identity:
100
26.6
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
26.6
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
33.3
100
20
N.A.
100
100
N.A.
N.A.
6.6
33.3
6.6
N.A.
20
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
9
34
42
25
9
0
0
% A
% Cys:
0
17
9
0
9
0
0
0
9
0
0
0
17
0
0
% C
% Asp:
42
0
17
0
17
42
0
0
0
17
9
0
0
0
9
% D
% Glu:
17
0
0
0
0
0
17
0
0
9
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
9
9
9
9
25
9
9
25
9
0
17
% G
% His:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
9
9
34
17
0
9
9
9
0
0
9
% L
% Met:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
34
9
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
9
9
9
0
9
0
0
17
0
9
42
9
50
42
% P
% Gln:
0
17
0
0
0
0
0
9
0
0
9
0
0
0
9
% Q
% Arg:
0
9
0
59
0
9
9
9
0
9
0
0
0
17
0
% R
% Ser:
9
0
0
9
0
0
9
9
0
9
0
0
42
17
17
% S
% Thr:
0
0
0
9
34
17
0
34
42
0
0
0
0
0
0
% T
% Val:
0
9
0
0
9
0
9
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _