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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD8
All Species:
13.94
Human Site:
Y308
Identified Species:
27.88
UniProt:
Q9H461
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H461
NP_114072.1
694
73300
Y308
I
D
M
E
R
F
K
Y
P
E
R
P
I
I
F
Chimpanzee
Pan troglodytes
XP_001142144
668
70462
Y288
I
D
M
E
R
F
K
Y
P
E
R
P
I
I
F
Rhesus Macaque
Macaca mulatta
XP_001096837
635
68033
A275
F
F
S
Q
D
E
R
A
F
T
V
F
W
I
G
Dog
Lupus familis
XP_545614
589
64543
S243
T
F
W
I
G
L
W
S
V
L
C
F
I
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61091
685
73197
Y305
I
D
M
E
R
F
K
Y
P
E
R
P
I
I
F
Rat
Rattus norvegicus
Q498S8
684
72990
Y304
I
D
M
E
R
F
K
Y
P
E
R
P
I
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA06
523
59263
E176
L
N
Y
K
F
L
G
E
K
D
C
A
A
P
C
Frog
Xenopus laevis
O93274
581
65360
F235
F
S
P
E
E
R
T
F
T
E
F
W
I
G
L
Zebra Danio
Brachydanio rerio
NP_570993
579
65231
D233
H
N
P
Y
F
T
Q
D
E
R
T
F
T
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
L327
W
I
A
L
W
S
G
L
C
F
C
S
T
L
M
Honey Bee
Apis mellifera
XP_397259
711
74000
L342
R
G
F
A
A
V
W
L
A
L
W
S
G
L
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188449
555
62346
G209
Y
Y
N
R
V
S
T
G
E
I
S
N
C
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
86.3
59.7
N.A.
95.5
95.8
N.A.
N.A.
40.6
70.6
71
N.A.
50.4
47.5
N.A.
53.4
Protein Similarity:
100
96.1
88.1
67.4
N.A.
95.9
96.2
N.A.
N.A.
52.5
75.6
76.5
N.A.
60.8
58.2
N.A.
63.2
P-Site Identity:
100
100
6.6
6.6
N.A.
100
100
N.A.
N.A.
0
20
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
20
6.6
N.A.
100
100
N.A.
N.A.
26.6
26.6
20
N.A.
6.6
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
9
9
0
0
9
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
25
0
9
0
17
% C
% Asp:
0
34
0
0
9
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
42
9
9
0
9
17
42
0
0
0
0
0
% E
% Phe:
17
17
9
0
17
34
0
9
9
9
9
25
0
0
42
% F
% Gly:
0
9
0
0
9
0
17
9
0
0
0
0
9
9
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
9
0
9
0
0
0
0
0
9
0
0
50
42
0
% I
% Lys:
0
0
0
9
0
0
34
0
9
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
0
17
0
17
0
17
0
0
0
17
9
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
17
9
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
34
0
0
34
0
9
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
34
9
9
0
0
9
34
0
0
0
0
% R
% Ser:
0
9
9
0
0
17
0
9
0
0
9
17
0
9
0
% S
% Thr:
9
0
0
0
0
9
17
0
9
9
9
0
17
0
17
% T
% Val:
0
0
0
0
9
9
0
0
9
0
9
0
0
0
0
% V
% Trp:
9
0
9
0
9
0
17
0
0
0
9
9
9
0
0
% W
% Tyr:
9
9
9
9
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _