Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL15 All Species: 18.18
Human Site: S197 Identified Species: 40
UniProt: Q9H469 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H469 NP_077302.3 300 32998 S197 R R G A G L R S L S L A V N A
Chimpanzee Pan troglodytes XP_001171119 388 42445 S285 R R G A G L R S L S L A V N A
Rhesus Macaque Macaca mulatta XP_001112383 300 32856 S197 R R G A G L R S L S L A V N A
Dog Lupus familis XP_543990 300 32965 S197 R R G A G L R S L S L A V N A
Cat Felis silvestris
Mouse Mus musculus Q91W61 300 33107 S197 R R G A G L R S L S L A V N A
Rat Rattus norvegicus Q9QZH7 276 30442 L200 G C G G L K A L F L K G C T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511287 309 34147 L170 R G S R L R S L S L A V N T N
Chicken Gallus gallus XP_426506 290 32414 L188 K C S R L K S L S L A V N A N
Frog Xenopus laevis NP_001079747 292 32995 L190 K S T R L K S L S L A V N A N
Zebra Danio Brachydanio rerio NP_998107 296 33509 L194 K C P E L R A L S V A V N A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036332 313 35058 V218 R K L N K L T V L S L A N T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77 98 96.6 N.A. 96.3 23.3 N.A. 53.4 62.6 55.3 58.6 N.A. 30.3 N.A. N.A. N.A.
Protein Similarity: 100 77 98.3 97.6 N.A. 97 44.6 N.A. 66.3 77.3 73.3 74 N.A. 46.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 6.6 0 0 0 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 6.6 6.6 6.6 6.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 46 0 0 19 0 0 0 37 55 0 28 46 % A
% Cys: 0 28 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 10 55 10 46 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 28 10 0 0 10 28 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 10 0 46 55 0 46 55 37 55 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 46 46 37 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 64 46 0 28 0 19 46 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 19 0 0 0 28 46 37 55 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 10 0 0 0 0 0 0 28 0 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 37 46 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _