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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSPYL3
All Species:
17.27
Human Site:
Y257
Identified Species:
54.29
UniProt:
Q9H489
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H489
NP_001003937
355
39573
Y257
N
K
V
I
V
K
E
Y
E
C
R
A
S
G
R
Chimpanzee
Pan troglodytes
XP_001153747
467
50774
Y369
N
K
V
I
V
K
E
Y
E
C
R
A
S
G
R
Rhesus Macaque
Macaca mulatta
XP_001108535
353
39243
Y255
N
K
V
I
M
K
E
Y
E
C
R
A
S
G
R
Dog
Lupus familis
XP_539094
359
38886
Y260
N
E
G
L
V
K
E
Y
E
R
R
S
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
O88852
379
42975
Y282
N
K
L
I
V
K
E
Y
E
V
R
S
S
G
R
Rat
Rattus norvegicus
Q9R1M3
334
37979
E218
S
I
I
S
N
Q
D
E
D
L
L
S
Y
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001124417
482
53749
F301
N
E
A
I
I
K
E
F
Q
Y
G
S
S
G
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25293
417
47866
K250
F
T
N
D
I
L
C
K
T
Y
F
Y
Q
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
89.3
47.9
N.A.
46.9
27.8
N.A.
N.A.
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.7
91.5
60.7
N.A.
60.6
45.6
N.A.
N.A.
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
80
0
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
40
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
38
0
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
38
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
13
0
13
0
0
0
0
0
0
% D
% Glu:
0
25
0
0
0
0
75
13
63
0
0
0
0
0
13
% E
% Phe:
13
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
0
0
13
0
0
75
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
13
63
25
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
75
0
13
0
0
0
0
0
13
0
% K
% Leu:
0
0
13
13
0
13
0
0
0
13
13
0
0
0
13
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
75
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
13
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
63
0
0
0
75
% R
% Ser:
13
0
0
13
0
0
0
0
0
0
0
50
75
0
0
% S
% Thr:
0
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% T
% Val:
0
0
38
0
50
0
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
0
25
0
13
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _