Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP1LC3A All Species: 34.85
Human Site: S12 Identified Species: 51.11
UniProt: Q9H492 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H492 NP_115903.1 121 14272 S12 R P F K Q R R S F A D R C K E
Chimpanzee Pan troglodytes XP_001159668 121 14274 S12 R T F Q Q R R S F S D R C K E
Rhesus Macaque Macaca mulatta XP_001086333 192 22656 T79 K T F K Q R R T F E Q R V E D
Dog Lupus familis XP_534391 121 14254 T12 R P F K Q R R T F A D R C K E
Cat Felis silvestris
Mouse Mus musculus Q91VR7 121 14254 S12 R P F K Q R R S F A D R C K E
Rat Rattus norvegicus Q62625 142 16375 S12 K T F K Q R R S F E Q R V E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511599 201 22095 P84 T S R G L S R P A A E R C K E
Chicken Gallus gallus XP_417327 121 14329 T12 R A F K Q R R T F A D R C K E
Frog Xenopus laevis NP_001080542 121 14335 S12 R P F K H R R S F A E R C A E
Zebra Danio Brachydanio rerio NP_955898 122 14500 T12 K T F K Q R R T F E Q R V E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395337 122 14352 S13 K S F K E R R S F A Q R V A D
Nematode Worm Caenorhab. elegans Q23536 130 15077 P22 P S F K E R R P F H E R Q K D
Sea Urchin Strong. purpuratus XP_783653 117 13908 E11 F K E R R S F E Q R R K D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYK7 121 13743 L12 S F K Q E H D L E K R R A E A
Baker's Yeast Sacchar. cerevisiae P38182 117 13608 F11 T F K S E Y P F E K R K A E S
Red Bread Mold Neurospora crassa Q8WZY7 121 14081 E12 F K D E H P F E K R K A E A E
Conservation
Percent
Protein Identity: 100 97.5 53.1 98.3 N.A. 100 69.7 N.A. 50.2 94.2 92.5 79.5 N.A. N.A. 63.1 54.6 69.4
Protein Similarity: 100 99.1 58.3 100 N.A. 100 78.8 N.A. 55.2 99.1 96.6 91.8 N.A. N.A. 81.9 75.3 85.1
P-Site Identity: 100 80 46.6 93.3 N.A. 100 53.3 N.A. 40 86.6 80 46.6 N.A. N.A. 53.3 46.6 6.6
P-Site Similarity: 100 93.3 73.3 100 N.A. 100 73.3 N.A. 46.6 93.3 86.6 73.3 N.A. N.A. 73.3 66.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 35.5 36.3 37.1
Protein Similarity: N.A. N.A. N.A. 62.8 60.3 62.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 7 44 0 7 13 19 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 % C
% Asp: 0 0 7 0 0 0 7 0 0 0 32 0 7 0 32 % D
% Glu: 0 0 7 7 25 0 0 13 13 19 19 0 7 32 57 % E
% Phe: 13 13 69 0 0 0 13 7 69 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 7 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 13 13 63 0 0 0 0 7 13 7 13 0 44 0 % K
% Leu: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 25 0 0 0 7 7 13 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 13 50 0 0 0 7 0 25 0 7 0 0 % Q
% Arg: 38 0 7 7 7 69 75 0 0 13 19 82 0 0 0 % R
% Ser: 7 19 0 7 0 13 0 38 0 7 0 0 0 0 7 % S
% Thr: 13 25 0 0 0 0 0 25 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 25 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _