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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP1LC3A
All Species:
50.3
Human Site:
Y99
Identified Species:
73.78
UniProt:
Q9H492
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H492
NP_115903.1
121
14272
Y99
S
T
P
I
A
D
I
Y
E
Q
E
K
D
E
D
Chimpanzee
Pan troglodytes
XP_001159668
121
14274
Y99
S
T
P
I
A
D
I
Y
E
Q
E
K
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001086333
192
22656
Y166
S
T
P
I
S
E
V
Y
E
S
E
K
D
E
D
Dog
Lupus familis
XP_534391
121
14254
Y99
S
T
P
I
A
D
I
Y
E
Q
E
K
D
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR7
121
14254
Y99
S
T
P
I
A
D
I
Y
E
Q
E
K
D
E
D
Rat
Rattus norvegicus
Q62625
142
16375
Y99
S
T
P
I
S
E
V
Y
E
S
E
R
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511599
201
22095
Y171
A
T
P
I
S
E
I
Y
E
Q
E
K
D
E
D
Chicken
Gallus gallus
XP_417327
121
14329
Y99
S
T
P
I
S
E
I
Y
E
Q
E
K
D
E
D
Frog
Xenopus laevis
NP_001080542
121
14335
Y99
S
T
P
I
L
D
I
Y
E
Q
E
K
D
E
D
Zebra Danio
Brachydanio rerio
NP_955898
122
14500
Y99
S
T
A
I
S
E
V
Y
E
R
E
R
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395337
122
14352
Y100
S
M
T
M
A
Q
L
Y
Q
R
E
Q
D
A
D
Nematode Worm
Caenorhab. elegans
Q23536
130
15077
Y109
S
M
S
M
S
N
L
Y
S
Q
E
R
D
P
D
Sea Urchin
Strong. purpuratus
XP_783653
117
13908
Y96
S
T
C
V
S
E
V
Y
Q
C
E
K
D
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK7
121
13743
E97
A
L
M
S
S
V
Y
E
E
K
K
D
D
D
G
Baker's Yeast
Sacchar. cerevisiae
P38182
117
13608
Q96
A
L
M
S
A
I
Y
Q
E
H
K
D
K
D
G
Red Bread Mold
Neurospora crassa
Q8WZY7
121
14081
E97
L
M
S
S
I
Y
E
E
H
K
D
E
D
G
F
Conservation
Percent
Protein Identity:
100
97.5
53.1
98.3
N.A.
100
69.7
N.A.
50.2
94.2
92.5
79.5
N.A.
N.A.
63.1
54.6
69.4
Protein Similarity:
100
99.1
58.3
100
N.A.
100
78.8
N.A.
55.2
99.1
96.6
91.8
N.A.
N.A.
81.9
75.3
85.1
P-Site Identity:
100
100
73.3
93.3
N.A.
100
66.6
N.A.
80
86.6
93.3
60
N.A.
N.A.
40
40
53.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
100
100
93.3
93.3
N.A.
N.A.
73.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
36.3
37.1
Protein Similarity:
N.A.
N.A.
N.A.
62.8
60.3
62.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
0
38
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
32
0
0
0
0
7
13
94
19
82
% D
% Glu:
0
0
0
0
0
38
7
13
75
0
82
7
0
63
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
0
63
7
7
44
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
13
57
7
0
0
% K
% Leu:
7
13
0
0
7
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
19
13
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
57
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
7
0
7
13
50
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
19
0
0
0
% R
% Ser:
75
0
13
19
50
0
0
0
7
13
0
0
0
0
0
% S
% Thr:
0
69
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
7
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
13
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _