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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNK1
All Species:
14.85
Human Site:
Y677
Identified Species:
40.83
UniProt:
Q9H4A3
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4A3
NP_061852.2
2382
250756
Y677
S
S
Q
Q
T
V
S
Y
G
S
Q
H
E
Q
A
Chimpanzee
Pan troglodytes
XP_508919
2382
250683
Y677
S
S
Q
Q
T
V
S
Y
G
S
Q
H
E
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095845
2384
250725
Y677
S
S
Q
Q
T
V
S
Y
G
S
Q
H
E
Q
A
Dog
Lupus familis
XP_853960
2389
250985
Y683
S
S
Q
Q
T
V
S
Y
G
S
Q
H
E
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P83741
2377
251030
R669
S
S
V
F
T
E
S
R
V
S
S
Q
Q
T
V
Rat
Rattus norvegicus
Q9JIH7
2126
225198
E457
P
E
V
K
E
I
I
E
G
C
I
R
Q
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508024
2425
260713
P745
S
Q
Q
G
V
I
Y
P
S
L
P
D
T
I
P
Chicken
Gallus gallus
XP_001235131
2380
248875
G685
S
Q
Q
T
V
S
Y
G
S
Q
H
D
Q
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666892
1684
182757
S15
P
S
K
N
T
N
G
S
S
S
D
T
L
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.8
89.9
N.A.
85.5
77.6
N.A.
31.4
69.4
N.A.
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
97.6
92.7
N.A.
89.4
81.2
N.A.
44.9
77.8
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
33.3
6.6
N.A.
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
26.6
N.A.
20
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
23
0
0
0
% D
% Glu:
0
12
0
0
12
12
0
12
0
0
0
0
45
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
12
12
56
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
45
0
0
0
% H
% Ile:
0
0
0
0
0
23
12
0
0
0
12
0
0
12
12
% I
% Lys:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% N
% Pro:
23
0
0
0
0
0
0
12
0
0
12
0
0
12
12
% P
% Gln:
0
23
67
45
0
0
0
0
0
12
45
12
34
45
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% R
% Ser:
78
67
0
0
0
12
56
12
34
67
12
0
0
0
0
% S
% Thr:
0
0
0
12
67
0
0
0
0
0
0
12
12
12
0
% T
% Val:
0
0
23
0
23
45
0
0
12
0
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
23
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _