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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNPEP All Species: 13.03
Human Site: S436 Identified Species: 23.89
UniProt: Q9H4A4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4A4 NP_064601.3 650 72596 S436 G D Q D Q F D S F L K A Y V H
Chimpanzee Pan troglodytes XP_001149557 650 72508 S436 G D Q D Q F D S F L K A Y V H
Rhesus Macaque Macaca mulatta XP_001107559 650 72476 N436 G D Q D Q F D N F L K A Y V H
Dog Lupus familis XP_547357 650 72248 T436 G D Q D R F D T F L K A Y V N
Cat Felis silvestris
Mouse Mus musculus Q8VCT3 650 72325 K436 G D Q D Q F D K F L K A Y V D
Rat Rattus norvegicus O09175 650 72601 K436 G D Q E Q F D K F L K A Y V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509819 759 84771 G554 G G P E I F L G F L K A Y V Q
Chicken Gallus gallus XP_419245 628 70471 A413 G D Q G K F D A F L Q A Y V E
Frog Xenopus laevis NP_001087880 612 69620 V407 D D F L K A Y V N K F K F Q S
Zebra Danio Brachydanio rerio NP_001002741 626 71245 T416 G D Q S R F D T F L K A Y V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793744 583 65836 K408 E Q K I T Q K K G F E F D H W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q10740 671 77334 P451 G G K A E F D P F I R H Y F K
Red Bread Mold Neurospora crassa Q7S785 614 68982 F405 G R E N F D K F I P Y Y F G K
Conservation
Percent
Protein Identity: 100 99 98.3 88.7 N.A. 88.9 88.4 N.A. 32.5 67.5 64.7 62 N.A. N.A. N.A. N.A. 49.8
Protein Similarity: 100 99.3 99 94 N.A. 94.3 94 N.A. 48 79.3 77.8 76.1 N.A. N.A. N.A. N.A. 67.3
P-Site Identity: 100 100 93.3 80 N.A. 86.6 80 N.A. 53.3 66.6 6.6 73.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 60 86.6 20 86.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.2 32.6
Protein Similarity: N.A. N.A. N.A. N.A. 48.2 51
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 60 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 8 0 0 0 70 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 70 0 39 0 8 70 0 0 0 0 0 8 0 16 % D
% Glu: 8 0 8 16 8 0 0 0 0 0 8 0 0 0 16 % E
% Phe: 0 0 8 0 8 77 0 8 77 8 8 8 16 8 0 % F
% Gly: 85 16 0 8 0 0 0 8 8 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 24 % H
% Ile: 0 0 0 8 8 0 0 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 16 0 16 0 16 24 0 8 62 8 0 0 16 % K
% Leu: 0 0 0 8 0 0 8 0 0 70 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 8 % N
% Pro: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 8 62 0 39 8 0 0 0 0 8 0 0 8 8 % Q
% Arg: 0 8 0 0 16 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 8 77 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _