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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
33.94
Human Site:
S146
Identified Species:
46.67
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S146
L
E
L
C
S
R
K
S
L
A
H
I
W
K
A
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S146
L
E
L
C
S
R
K
S
L
A
H
I
W
K
A
Dog
Lupus familis
XP_532604
646
71462
S146
L
E
L
C
S
R
K
S
L
A
H
I
W
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S147
L
E
L
C
S
R
K
S
L
A
H
I
W
K
A
Rat
Rattus norvegicus
Q9R011
615
68782
E128
K
A
R
H
T
L
L
E
P
E
V
R
Y
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
S275
L
E
Y
C
S
R
R
S
M
A
H
I
L
K
A
Chicken
Gallus gallus
XP_422425
639
71988
S130
L
E
H
C
S
R
K
S
L
A
H
I
W
K
A
Frog
Xenopus laevis
P70032
598
68193
S128
L
E
L
C
R
R
R
S
L
L
E
L
H
K
R
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
S127
L
E
L
C
S
R
K
S
L
A
H
I
W
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
R117
M
M
E
L
H
K
R
R
K
S
I
T
E
F
E
Honey Bee
Apis mellifera
XP_396707
575
66141
K116
M
E
L
H
K
R
R
K
A
L
T
E
C
E
T
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
T132
H
K
R
R
K
A
V
T
E
P
E
A
R
Y
F
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
E124
K
R
R
K
A
I
T
E
P
E
T
R
Y
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
T132
I
K
R
R
K
R
L
T
E
I
E
V
Q
C
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S165
L
E
I
C
P
N
G
S
L
M
E
L
L
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
73.3
93.3
53.3
100
N.A.
0
20
0
0
P-Site Similarity:
100
0
100
100
N.A.
100
13.3
N.A.
86.6
93.3
66.6
100
N.A.
26.6
40
13.3
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
0
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
6
6
0
0
6
42
0
6
0
0
42
% A
% Cys:
0
0
0
53
0
0
0
0
0
0
0
0
6
6
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
59
6
0
0
0
0
12
12
12
24
6
6
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
6
% F
% Gly:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% G
% His:
6
0
6
12
6
0
0
0
0
0
42
0
6
0
0
% H
% Ile:
6
0
6
0
0
6
0
0
0
6
6
42
0
0
0
% I
% Lys:
12
12
0
6
18
6
36
6
6
0
0
0
0
53
0
% K
% Leu:
53
0
42
6
0
6
12
0
48
12
0
12
12
0
6
% L
% Met:
12
6
0
0
0
0
0
0
6
6
0
0
0
0
6
% M
% Asn:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
6
0
0
0
12
6
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
6
24
12
6
59
24
6
0
0
0
12
6
0
12
% R
% Ser:
0
0
0
0
42
0
0
53
0
6
0
0
0
0
0
% S
% Thr:
0
0
0
0
6
0
6
12
0
0
12
6
0
0
6
% T
% Val:
0
0
0
0
0
0
6
0
0
0
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% W
% Tyr:
0
0
6
0
0
0
0
0
0
0
0
0
12
12
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _