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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
27.27
Human Site:
S282
Identified Species:
37.5
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S282
V
H
Y
T
L
P
A
S
L
S
L
P
A
R
Q
Chimpanzee
Pan troglodytes
XP_513131
442
49225
P99
G
T
P
N
Y
V
A
P
E
V
L
L
R
Q
G
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S282
V
H
Y
T
L
P
A
S
L
S
L
P
A
R
Q
Dog
Lupus familis
XP_532604
646
71462
S282
V
H
Y
T
L
P
A
S
L
S
L
P
A
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S283
V
H
Y
T
L
P
A
S
L
S
L
P
A
R
Q
Rat
Rattus norvegicus
Q9R011
615
68782
S251
V
H
Y
T
L
P
A
S
L
S
L
P
A
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
S411
A
R
Y
T
M
P
S
S
L
L
A
P
A
K
H
Chicken
Gallus gallus
XP_422425
639
71988
F266
V
D
Y
I
L
P
T
F
L
S
L
P
A
R
H
Frog
Xenopus laevis
P70032
598
68193
R253
C
L
K
E
T
Y
M
R
I
K
K
N
E
Y
S
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
S263
V
K
Y
S
L
P
S
S
L
T
P
S
A
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
I235
L
K
D
T
Y
S
K
I
K
K
C
E
Y
R
V
Honey Bee
Apis mellifera
XP_396707
575
66141
K234
K
E
T
Y
A
R
I
K
Q
V
Q
Y
K
I
P
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
S255
N
N
Y
V
I
P
T
S
A
S
A
A
A
S
Q
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
R243
R
I
K
R
N
E
Y
R
V
P
S
H
V
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
H257
C
E
Y
S
F
P
D
H
V
S
V
S
D
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
F98
Y
V
K
G
G
E
L
F
D
K
V
S
K
G
K
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
D303
R
D
F
S
F
P
R
D
K
P
I
S
D
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
46.6
66.6
0
46.6
N.A.
13.3
0
40
0
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
66.6
66.6
6.6
80
N.A.
20
0
53.3
6.6
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
20
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
6
0
36
0
6
0
12
6
53
0
6
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% C
% Asp:
0
12
6
0
0
0
6
6
6
0
0
0
12
0
0
% D
% Glu:
0
12
0
6
0
12
0
0
6
0
0
6
6
6
0
% E
% Phe:
0
0
6
0
12
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
6
0
0
6
6
0
0
0
0
0
0
0
0
6
12
% G
% His:
0
30
0
0
0
0
0
6
0
0
0
6
0
0
12
% H
% Ile:
0
6
0
6
6
0
6
6
6
0
6
0
0
6
0
% I
% Lys:
6
12
18
0
0
0
6
6
12
18
6
0
12
6
12
% K
% Leu:
6
6
0
0
42
0
6
0
48
6
42
6
0
0
0
% L
% Met:
0
0
0
0
6
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
0
6
6
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
6
0
0
65
0
6
0
12
6
42
0
0
6
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
6
0
0
12
36
% Q
% Arg:
12
6
0
6
0
6
6
12
0
0
0
0
6
42
0
% R
% Ser:
0
0
0
18
0
6
12
48
0
48
6
24
0
12
6
% S
% Thr:
0
6
6
42
6
0
12
0
0
6
0
0
0
6
6
% T
% Val:
42
6
0
6
0
6
0
0
12
12
12
0
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
59
6
12
6
6
0
0
0
0
6
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _