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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
31.21
Human Site:
S326
Identified Species:
42.92
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S326
T
P
D
R
L
P
I
S
S
C
V
T
V
P
D
Chimpanzee
Pan troglodytes
XP_513131
442
49225
K143
K
E
T
Y
R
C
I
K
Q
V
H
Y
T
L
P
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S326
T
P
D
R
L
P
I
S
S
C
V
T
V
P
D
Dog
Lupus familis
XP_532604
646
71462
S326
T
P
D
R
L
P
V
S
S
C
V
T
V
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S327
T
P
D
R
L
P
V
S
S
C
V
T
V
P
D
Rat
Rattus norvegicus
Q9R011
615
68782
S295
T
P
D
R
L
P
V
S
S
C
V
T
V
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
S455
T
P
E
R
L
S
S
S
C
C
H
T
V
P
D
Chicken
Gallus gallus
XP_422425
639
71988
S310
P
E
K
L
P
P
S
S
C
V
M
A
P
E
L
Frog
Xenopus laevis
P70032
598
68193
T297
L
L
N
D
E
F
F
T
S
G
Y
I
P
S
R
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
S307
T
P
E
K
L
P
P
S
S
C
V
M
V
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
G279
L
N
F
E
F
L
K
G
S
K
V
P
M
F
L
Honey Bee
Apis mellifera
XP_396707
575
66141
G278
K
D
P
F
F
T
C
G
F
M
P
L
S
L
P
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
S299
M
P
A
R
L
P
V
S
C
L
T
M
V
P
H
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
Q287
T
T
G
Y
L
P
P
Q
L
P
T
T
C
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
L301
A
N
N
I
P
K
F
L
P
A
S
T
L
A
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
L142
L
K
P
E
N
L
L
L
D
E
N
G
D
L
K
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S347
T
F
P
P
S
I
P
S
T
V
M
S
E
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
66.6
13.3
6.6
66.6
N.A.
13.3
0
46.6
26.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
73.3
20
20
86.6
N.A.
20
0
53.3
26.6
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
0
0
0
0
6
0
6
0
12
0
% A
% Cys:
0
0
0
0
0
6
6
0
18
42
0
0
6
0
6
% C
% Asp:
0
6
30
6
0
0
0
0
6
0
0
0
6
0
36
% D
% Glu:
0
12
12
12
6
0
0
0
0
6
0
0
6
6
6
% E
% Phe:
0
6
6
6
12
6
12
0
6
0
0
0
0
6
0
% F
% Gly:
0
0
6
0
0
0
0
12
0
6
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
6
% H
% Ile:
0
0
0
6
0
6
18
0
0
0
0
6
0
0
0
% I
% Lys:
12
6
6
6
0
6
6
6
0
6
0
0
0
0
6
% K
% Leu:
18
6
0
6
53
12
6
12
6
6
0
6
6
24
12
% L
% Met:
6
0
0
0
0
0
0
0
0
6
12
12
6
0
0
% M
% Asn:
0
12
12
0
6
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
6
48
18
6
12
53
18
0
6
6
6
6
12
48
18
% P
% Gln:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% Q
% Arg:
0
0
0
42
6
0
0
0
0
0
0
0
0
0
6
% R
% Ser:
0
0
0
0
6
6
12
59
48
0
6
6
6
6
0
% S
% Thr:
53
6
6
0
0
6
0
6
6
0
12
48
6
0
6
% T
% Val:
0
0
0
0
0
0
24
0
0
18
42
0
48
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
6
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _